The purpose of this project is to identify and target barriers faced by rural endometrial cancer patients in order to develop a patient navigation intervention. Rural residents with endometrial cancer, the the most prevalent gynecologic cancer in the US, have higher odds of mortality than urban endometrial cancer patients. As the number of new endometrial cancer cases is expected to increase 50% by 2030, this urban-rural disparity is expected to continue widening.

The purpose of this project is to identify and target barriers faced by rural endometrial cancer patients in order to develop a patient navigation intervention. Rural residents with endometrial cancer, the most prevalent gynecologic cancer in the US, have higher odds of mortality than urban endometrial cancer patients. As the number of new endometrial cancer cases is expected to increase 50% by 2030, this urban-rural disparity is expected to continue widening.

The purpose of this study is to create a registry that will collect clinical data from participants attending UNC Hospitals who may present with metastatic cancer and are evaluated to receive radiation therapy. We hope to create a registry that future studies can pull from to study the impacts of radiation therapy on patient cancer outcomes.

To evaluate the safety and efficacy of streamlining Yttrium-90 radioembolization workflow for patients with small Hepatocellular Carcinoma (HCC) (<5cm) that have no aggressive features on baseline imaging.

Purpose: To develop, assess, and refine a brief electronic patient-reported outcome (ePRO) tool that can be completed weekly by patients with newly diagnosed breast and colorectal cancer to self-report progress from diagnosis to treatment initiation.

Cancer caregivers experience high levels of stress related to the caregiving role, particularly for rural caregivers. The purpose of this study is to assess the acceptability and preliminary effect of enCompass Carolina, a social support program for caregivers of rural-dwelling patients with cancer.

The purpose of this study is to evaluate the efficacy of sodium thiosulfate (STS) infusion administered during cisplatin-containing chemotherapy cycles in reducing hearing loss in children with newly-diagnosed average-risk medulloblastoma.

The purpose of this study is to create an educational video on colorectal cancer, screening and prevention, and clinical trials in Spanish in order to demonstrate a correlation between increased education and increased willingness to participate in clinical trials in the Latinx populations through local churches.

Research with blood and cells (generally called specimens) can help researchers understand how the human body works. Research can also answer other questions by using specimens. Researchers may develop new tests to find diseases, or new ways to treat diseases. In the future, research may help to develop new products, such as drugs. You are being asked for permission to use your biospecimens and medical records for this study. Using your biospecimens, researchers may be able to detect CAR-T cells in your body after you receive the CAR-T treatment. The purpose of this study is to validate the detection method of CAR-T cells in the blood to advance CAR-T therapy development.

The purpose of this study is to test the safety of the two study drugs, venetoclax and selinexor, and to find the highest dose of venetoclax and selinexor that can be given safely when it is combined with chemotherapy drugs (cytarabine or cytarabine and fludarabine). This study tests different doses of venetoclax and selinexor to see which dose is safer in children with leukemia.