This is a study evaluating whether the use of an electronic web-based tool containing surveys could support patients and doctors make better treatment decisions together. New patients, 60 years or older, will be randomized to either receive the tool or not. Surveys will be collected from patients about their experience in making treatment decisions to evaluate whether the tool was beneficial.

The purpose of this study is to evaluate the efficacy of sodium thiosulfate (STS) infusion administered during cisplatin-containing chemotherapy cycles in reducing hearing loss in children with newly-diagnosed average-risk medulloblastoma.

To evaluate the safety and efficacy of streamlining Yttrium-90 radioembolization workflow for patients with small Hepatocellular Carcinoma (HCC) (<5cm) that have no aggressive features on baseline imaging.

You are being asked to participate in this study because you have an appointment at UNC Urology, and you have been diagnosed with prostate cancer. The purpose of this research study is to learn how either cryosurgery or prostatectomy procedures change the inflammatory response within the body. To do this, we will draw blood and analyze it for signs of inflammation before and after your standard of care procedure.

Cancer caregivers experience high levels of stress related to the caregiving role, particularly for rural caregivers. The purpose of this study is to assess the acceptability and preliminary effect of enCompass Carolina, a social support program for caregivers of rural-dwelling patients with cancer.

We are surveying families of pediatric hematology/oncology patients to find out their interest in and use of integrative and complementary health practices.

The purpose of this study is to create an educational video on colorectal cancer, screening and prevention, and clinical trials in Spanish in order to demonstrate a correlation between increased education and increased willingness to participate in clinical trials in the Latinx populations through local churches.

Research with blood and cells (generally called specimens) can help researchers understand how the human body works. Research can also answer other questions by using specimens. Researchers may develop new tests to find diseases, or new ways to treat diseases. In the future, research may help to develop new products, such as drugs. You are being asked for permission to use your biospecimens and medical records for this study. Using your biospecimens, researchers may be able to detect CAR-T cells in your body after you receive the CAR-T treatment. The purpose of this study is to validate the detection method of CAR-T cells in the blood to advance CAR-T therapy development.

The purpose of this study is to test the safety of the two study drugs, venetoclax and selinexor, and to find the highest dose of venetoclax and selinexor that can be given safely when it is combined with chemotherapy drugs (cytarabine or cytarabine and fludarabine). This study tests different doses of venetoclax and selinexor to see which dose is safer in children with leukemia.

Black men are diagnosed with prostate cancer more often than white men, and more commonly die from this disease. Care for advanced prostate cancer has improved a great deal over the past ten years, but these differences have continued. In order to improve equity in cancer care, we want to determine who is not getting the highest quality of care and whether race is associated with differences in care. Our study will ask Black and White men about their experiences with cancer care - if they trusted their doctors, how well their doctors communicated with them, and if they were satisfied with the care they received. We will ask about the challenges they experienced in receiving care, and what might have helped them get better care. We will use these results to design a better way to deliver care.