To initiate and evaluate a multilevel navigation intervention to promote lung cancer screening among Black/African Americans and to develop a population-based biorepository for future research in understanding biological risk factors for poor lung cancer outcomes among Black/African Americans

The purpose of this study is to to determine the efficacy (as measured by Neurocognitive testing) of oral memantine administered for a period of 6 months, when compared to placebo, in children ages 4-18 receiving cranial or craniospinal radiotherapy for primary central nervous system tumors.

You are being asked to participate in this research study because you have a type of tumor called a Central Nervous System (CNS) tumor, and you are scheduled to have surgery to remove this tumor. The study team wants to use left-over tumor samples from this surgery to study your tumor and test new ways to fight it.

This study is being done to answer the following question: Do two different anti-cancer drugs, paclitaxel (PTX) and pegylated liposomal doxorubicin (PLD) have similar effects on treating KS in PLWH in sub-Saharan Africa? We are doing this study because we want to find out if one of these approaches, PTX or PLD, is better than the other for KS. Both drugs may be given as part of the usual approach for your KS. The usual approach is defined as care most people get for KS.

This is an exploratory study in cancer biomarker research, hoping to identify cell-signaling using DNA, in patients with SCLC.

The purpose of this study is to evaluate a new test being developed by Tempus for patients with Non-Small Cell Lung Cancer (NSCLC). The goal of this new test is to predict the likelihood of a patient's cancer coming back after treatment, and to further explore changes in patient's tumors throughout treatment to see how they respond.

The purpose of this study is to determine if it is possible to identify biomarkers that tell us what type of response a person with metastatic breast cancer (MBC) will have to "antibody-drug conjugates" (ADCs).

The purpose of this study is to determine the safety of the addition of universal donor, expanded NK cells to gemcitabine/docetaxel for treatment of relapsed and refractory sarcomas.

The purpose of this study is to assess the efficacy as well as safety and tolerability of a new drug called padsevonil that will be given in one of 3 different doses in addition to your current epilepsy treatment that may consist of 1-3 antiepileptic drugs. The study also aims to see how safe padsevonil is compared to placebo and how well your body can tolerate it.

To initiate and evaluate a multilevel navigation intervention to promote lung cancer screening among Black/African Americans