Do you have head and neck cancer or soft tissue sarcoma? Are you planning to have surgery to remove your tumor? You may be able to participate in a research study to determine which therapies may be best for future patients. Compensation provided.

The purpose of this study is to better understand how young adults (ages 18 - 39) who have had cancer use entertainment media during and after cancer treatment.

To evaluate the effectiveness of using a combination of pembrolizumab and olaparib when given before and after standard chemoradiation therapy in treating locally advanced head and neck squamous cell carcinoma

The purpose of this research study is to deliver 6 months of 1:1 health coaching to cancer patients being treated at UNC Cancer Hospital. This program hopes to improve patient's self-confidence and satisfaction with how they feel and what they are able to do day-to-day. This includes exercising, support for healthy eating, emotional and social needs. Health coaching means you will receive weekly phone calls and emails from a trained coach.

Will you be treated for Locally Advanced Head and Neck Squamous Cell Carcinoma? Have you been cancer free for at least two years after previous treatment? If so, you may eligible to participate in a clinical research trial aimed to measure the level of ctDNA in the blood before and after treatment.

This study seeks to better understand the unmet needs and care preferences of young adult cancer patients and their caregivers. Interviews to gather this information will be used to tailor an existing, evidence-based patient navigation program to these needs and preferences.

The overall objective of this project is to examine differences in performance fatigability and contributing mechanisms between firefighters in cancer remission and healthy firefighter controls. Findings from this research project will inform future interventions to reduce CRF in firefighters in cancer remission.

The purpose of this study is to measure the effect of 30 mg RE104 on adjustment disorder symptoms (depressed mood or anxiety) compared to 1.5 mg RE104 in participants with cancer or other illnesses in order to decrease these symptoms.

We are collecting blood and optionally stool, bone marrow or tissue samples from patients who received cell therapy or a stem cell transplant to treat cancer. This will help understand how the immune system recovers after cell therapy or stem cell transplant and how it may relate to patient outcomes.

The goal of the study is to determine why some men and women get certain types of head and neck (mouth or throat) cancer, and others do not. If we can identify underlying causes of head and neck cancer, we can determine ways to prevent it from occurring. Collection and analysis of medical records and tumor biology may also lead to more effective treatments and lower the death rate from this disease.