To evaluate the safety and efficacy of streamlining Yttrium-90 radioembolization workflow for patients with small Hepatocellular Carcinoma (HCC) (<5cm) that have no aggressive features on baseline imaging.
The main purpose of this clinical research study is to assess the safety, tolerability, efficacy (the ability of the study drug to produce the desired anti cancer effect), PK] and PD of GHF009X2101 the study drug in patients with relapsed or refractory hematologic malignancies including AML, CLL, SLL or other lymphomas [including other leukemia].
To see if women who had breast cancer at ages 18-40 were able to successfully lactate and breastfeed after lumpectomy and radiation treatment afterwards.
Aim 1: To co-develop the "Patient-Centered Pharmacy Pathway for Oral Chemotherapy" (P3OC) components through stakeholder engagement by conducting a modified Delphi panel with pharmacists, physicians, and other oncology healthcare providers (36,37) to determine key symptoms to assess during oral chemotherapy. Aim 2: To conduct usability testing(38,39) of the P3OC EHR Smart Form, verbal PROM, and report/dashboard with pharmacists.
To establish the recommended Phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for 5 consecutive days.
This study will evaluate the safety and tolerability of EG 70, a gene therapy, which is given inside the bladder, and its effectiveness on eliminating bladder tumors in patients with NMIBC who have failed BCG therapy and have been recommended to have their bladder removed. Giving the study drug inside the bladder is to expose cells in the lining of the bladder, including your cancerous cells, to genes that may cause an immune response inside the bladder and kill the tumor cells.
To discover how different forms of radiation affect the sleep, mood, and social function of adults with brain cancer. Doctors have suspected that these patients may be getting worse sleep, but no one has studied it. Since sleep is important in recovery and overall body function, understanding how radiation changes it will lead to a greater clinical understanding of the treatment.
Cancer information is widely shared on social media, however not all information is true. We aim to explore how social media designs, including in platform prompts and messages, can encourage individuals in cancer care networks to think about the quality and accuracy of cancer information shared online. This innovative work will establish the feasibility, infrastructure, and protocols to test social media designs (prompts, messages) among adults in cancer care networks.
Purpose: to establish a Registry of pediatric patients treated with proton radiation therapy. Participants: Patients who are less than or equal to 21 years old at time of treatment start and treated with radiation therapy at one of the participating centers. Procedures (methods): This Proton and Photon Consortium Registry (PPCR) enrolls children treated with radiation therapy to form an expansive description of the pediatric population that receives protons and to better catalogue the benefits of protons, in this cohort. The data will also be used to evaluate practice differences and help facilitate collaborative research across the various radiation centers. The PPCR collects an expanded set of demographic and clinical data that will enhance the practice data that many participating radiation centers already collect in their routine operations. The PPCR has been expanded to include a photon-treated control group, helping to facilitate comparative effectiveness analysis.
The goal of this survey is to evaluate othe current practice across institutions in the United States by surveying Pathologists and Pathologists' Assistants about their approach to pathologic evaluation of bladder cancer specimens (cystectomies). This information would provide useful information about best practices for gross examination of post-NAC cystectomies and help standardize practice between institutions.