This project is a randomized clinical trial (study that randomly assigns participants to one arm to fairly understand outcomes) that aims to assess if information from gene expression classifier (GEC) testing is helpful for both patients and their doctors in the management of care for newly diagnosed prostate cancer patients.
This study will investigate how mechanical properties of breast tissue, such as stiffness, viscosity, and anisotropy, are related to breast tumor malignancy and response to chemotherapy. The study uses ultrasound imaging to measure these mechanical properties non-invasively in human subjects.
The purpose of this research study is to monitor how well patients with fatty liver disease can follow clinician-recommended diet and exercise before their liver surgery. Our goal is to understand patient adherence to weight-related goals, weight loss, physical activity, and improved liver health. You are being asked to be in the study because you are a patient with fatty liver disease planning to have liver surgery.
Our team developed a calculator to help oncologists better estimate prognosis in patients with metastatic breast cancer (MBC). Using this information, our team developed a prognostic calculator to predict risk of death within 30 days for patients with MBC. For this information to impact care, it will have to be used in clinical practice. In order to increase the likelihood of successful adoption of the calculator into clinical practice, we will study its implementation and evaluate its impact. In this study, we will seek the input of doctors, nurses, and advance practice providers who care for patients with MBC to better understand the factors that encourage and dissuade discussion of prognosis and use of such a prognostic tool.
Purpose:This is a two-arm preliminary efficacy RCT in 120 participants testing a 6-week home-based walking and progressive resistance exercise program (EXCAP©®) vs. standard care on CIPN, interoception, and inflammation. Participants: This study will enroll 120 participants receiving neurotoxic chemotherapy or have completed neurotoxic chemotherapy in the past nine months (i.e., taxane-, platinum-, vinca alkaloid-, epothilone-, or proteasome inhibitor-based chemotherapy). Procedures (methods): Participants will complete questionnaires, clinical assessments, and a blood draw at two time points: pre-intervention (week 0, T1) and post-intervention (approximately week 6, T2).
Colontown is an online community of more than 100 private Facebook groups for colorectal cancer patients, survivors, and care partners. The purpose of this study is document and analyze Colontown members' engagement practices and perceptions of patient empowerment, to determine how online communities can support patients and caregivers in CRC management.
The main objective is to glean stakeholders' perspectives about implementing and disseminating an intervention for Black women with breast cancer and their female support people into clinical care.
Using carefully constructed case vignettes and a survey of oncology providers across a spectrum of settings, we sought to characterize early trends in internalization of the girentuximab PET-CT into care.
This is a study to assess patient, provider, and pharmacist perceptions of delivering FIT kits for colorectal cancer screening in pharmacy settings.
The aim of this study for low and standard risk germ cell tumor (GCT) patients is to minimize toxicity by reducing therapy while maintaining current survival rates. The trial will eliminate chemotherapy for low risk patients who are likely cured with surgery and will observe the salvage rates among those who recur.