Research with blood and cells (generally called specimens) can help researchers understand how the human body works. Research can also answer other questions by using specimens. Researchers may develop new tests to find diseases, or new ways to treat diseases. In the future, research may help to develop new products, such as drugs. You are being asked for permission to use your biospecimens and medical records for this study. Using your biospecimens, researchers may be able to detect CAR-T cells in your body after you receive the CAR-T treatment. The purpose of this study is to validate the detection method of CAR-T cells in the blood to advance CAR-T therapy development.

The purpose of this study is to create an educational video on colorectal cancer, screening and prevention, and clinical trials in Spanish in order to demonstrate a correlation between increased education and increased willingness to participate in clinical trials in the Latinx populations through local churches.

Cancer caregivers experience high levels of stress related to the caregiving role, particularly for rural caregivers. The purpose of this study is to assess the acceptability and preliminary effect of enCompass Carolina, a social support program for caregivers of rural-dwelling patients with cancer.

The expected outcome of this proposal is a novel care pathway delivered by pharmacists to improve side effects during oral chemotherapy for patients, a known barrier to adherence, and ultimately to prevent progression and early mortality. Our long-term goal for P3OC is to develop and test new dashboard features to optimize pharmacy care, meet future needs for value-based payment models, and improve patient outcomes.

To evaluate the safety and tolerability of ALX148 in combination with enfortumab vedotin in subjects with previously treated locally advanced or metastatic urothelial carcinoma. To determine the maximum tolerated dose (MTD) and the recommended Phase 2 dose (RP2D) of ALX148 in combination with enfortumab vedotin.

Purpose: To develop, assess, and refine a brief electronic patient-reported outcome (ePRO) tool that can be completed weekly by patients with newly diagnosed breast and colorectal cancer to self-report progress from diagnosis to treatment initiation.

The purpose of this project is to identify and target barriers faced by rural endometrial cancer patients in order to develop a patient navigation intervention. Rural residents with endometrial cancer, the most prevalent gynecologic cancer in the US, have higher odds of mortality than urban endometrial cancer patients. As the number of new endometrial cancer cases is expected to increase 50% by 2030, this urban-rural disparity is expected to continue widening.

The purpose of this project is to identify and target barriers faced by rural endometrial cancer patients in order to develop a patient navigation intervention. Rural residents with endometrial cancer, the the most prevalent gynecologic cancer in the US, have higher odds of mortality than urban endometrial cancer patients. As the number of new endometrial cancer cases is expected to increase 50% by 2030, this urban-rural disparity is expected to continue widening.

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.

We are conducting this study to better understand the relationship between access to care, financial stress and health related quality of life among cancer patients in NC who live in rural areas. We will be interviewing 30 rural cancer patients to learn about their cancer experience and we will be reviewing previously completed surveys about their distress and coping behaviors.