Research with blood and cells (generally called specimens) can help researchers understand how the human body works. Research can also answer other questions by using specimens. Researchers may develop new tests to find diseases, or new ways to treat diseases. In the future, research may help to develop new products, such as drugs. You are being asked for permission to use your biospecimens and medical records for this study. Using your biospecimens, researchers may be able to detect CAR-T cells in your body after you receive the CAR-T treatment. The purpose of this study is to validate the detection method of CAR-T cells in the blood to advance CAR-T therapy development.

The purpose of this study is to develop and validate an Artificial intelligence (AI)-based tissue sample analysis tool that can predict response & progression rates to chemotherapy in intermediate-risk (IR) and high-risk (HR) Non-muscle invasive bladder cancer (NMIBC) patients. This study will use AI-based tissue sample analysis as a possible tool to help predict which patients are at high-risk for cancer recurrence and progression after surgery and chemotherapy treatment. Specimens will be obtained for each patient before treatment and at the 12, 24, & 36 month follow-up to be analyzed using the AI-based tool.

The purpose of this study is to test the safety of the two study drugs, venetoclax and selinexor, and to find the highest dose of venetoclax and selinexor that can be given safely when it is combined with chemotherapy drugs (cytarabine or cytarabine and fludarabine). This study tests different doses of venetoclax and selinexor to see which dose is safer in children with leukemia.

Black men are diagnosed with prostate cancer more often than white men, and more commonly die from this disease. Care for advanced prostate cancer has improved a great deal over the past ten years, but these differences have continued. In order to improve equity in cancer care, we want to determine who is not getting the highest quality of care and whether race is associated with differences in care. Our study will ask Black and White men about their experiences with cancer care - if they trusted their doctors, how well their doctors communicated with them, and if they were satisfied with the care they received. We will ask about the challenges they experienced in receiving care, and what might have helped them get better care. We will use these results to design a better way to deliver care.

To establish the recommended Phase II dose of a flavored preparation of orally administered irinotecan (VAL-413) when given in combination with temozolomide for 5 consecutive days.

We would like to help patients identify what is important to them, i.e., their values, and support communicating that to their caregivers and healthcare providers. We are trying to create a tool that will make it easier to share what is most important to patients with metastatic breast cancer and their caregivers, with the patient's oncology healthcare provider.

The purpose of the study is to determine how the Cancer Prevention and Control Research Network (CPCRN) researchers and their community partners are operationalizing the nine health equity Principles adopted by the network. The examples, acquired through in-depth interviews, will be used to develop a technical assistance toolkit for CPCRN and the general research community.

We are determining whether upper extremity function improves after surgery for patients presenting with upper extremity lymphedema.

The study purpose is to find out if (a) it's possible to deliver healthy frozen meals to homes of children receiving chemotherapy, and (b) the meals are acceptable to the children and their families.

The goal of this study is to help CAPRICORN understand the needs of primary care clinics in North Carolina that provide free or low-cost healthcare. We will focus on how these clinics can offer cancer screening events to people in the community. To do this, we will create and use a survey to learn more about the needs of 3-4 clinics in North Carolina. Our findings will be shared in a report that includes suggestions for how CAPRICORN can grow over the next five years.