The purpose of this study is to identify specific barriers to preventing a late stage cancer diagnosis within communities identified in North Carolina as having a higher rate of advanced cancer diagnoses.
Cancer caregivers experience high levels of stress related to the caregiving role, particularly for rural caregivers. The purpose of this study is to assess the acceptability and preliminary effect of enCompass Carolina, a social support program for caregivers of rural-dwelling patients with cancer.
Purpose:This is a two-arm preliminary efficacy RCT in 120 participants testing a 6-week home-based walking and progressive resistance exercise program (EXCAP©®) vs. standard care on CIPN, interoception, and inflammation. Participants: This study will enroll 120 participants receiving neurotoxic chemotherapy or have completed neurotoxic chemotherapy in the past nine months (i.e., taxane-, platinum-, vinca alkaloid-, epothilone-, or proteasome inhibitor-based chemotherapy). Procedures (methods): Participants will complete questionnaires, clinical assessments, and a blood draw at two time points: pre-intervention (week 0, T1) and post-intervention (approximately week 6, T2).
The purpose of this study is to develop a prospective longitudinal cohort/registry of lymphoma patients in Malawi to address a lack of prospective longitudinal data related to lymphoma in sub-Saharan Africa, and to serve as a foundation for developing optimal treatment strategies in this challenging environment.
To create digital tools to support young adult cancer survivors completing active treatment and transitioning into survivorship care.
The purpose of this study is to understand how your gut plays a role in how well CAR T cell therapy works. Your gut is home to bacteria, which we call the gut microbiome. The gut microbiome can send signals to your immune cells, which may impact how well and how long CAR T cell therapy will last. We can find out what type of bacteria are in your gut microbiome by studying your stool. We can understand more about the signals sent to the immune system by studying your blood. We will ask for stool and blood at the same time points throughout your treatment. We will study the identities and function of the bacteria and immune cells to understand more about how these signals work during CAR T cell treatment.
The primary objective of this repository is to make blood samples available for research studies related to histocompatibility and HC transplantation or other cellular therapy.
Screening tool to collect broader demographic and clinical data. Enhance understanding of site specific and trial specific accrual barriers.
The purpose of this study is to learn how having specific help over a period of time (financial navigation) can help reduce your distress related to the cost of cancer. You will complete a survey to see if you have financial distress. If you have financial distress, you will then fill out a few more surveys and be asked more details about your current financial situation to determine what programs could be helpful for you. The surveys can be completed in person, by email, or over the phone. The navigator can help you complete the surveys if needed. After that, depending on your needs, you will have 1-6 appointments with the financial navigator over a period of 2 weeks -4 months. Risks to you are small due to the educational nature of this study. They may include mild emotional distress while talking about your cancer and financial experiences. Benefits
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications. This protocol will allow access to cord blood units that are unlicensed.