This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications. This protocol will allow access to cord blood units that are unlicensed.

The purpose of this study is to develop a prospective longitudinal cohort/registry of lymphoma patients in Malawi to address a lack of prospective longitudinal data related to lymphoma in sub-Saharan Africa, and to serve as a foundation for developing optimal treatment strategies in this challenging environment.

Screening tool to collect broader demographic and clinical data. Enhance understanding of site specific and trial specific accrual barriers.

we will be conducting 60-minute interviews with young adults to hear about social connections (in person and online) and cancer support on social media

The purpose of this study is to collect evidence for or against the addition of olanzapine to standard nausea/vomiting prophylaxis in children receiving cyclophosphamide-based Bone Marrow Transplant conditioning. Its findings will be generalizable to children receiving other types of chemotherapy that have the potential to increase nausea/vomiting.

The purpose of this study is to understand how your gut plays a role in how well CAR T cell therapy works. Your gut is home to bacteria, which we call the gut microbiome. The gut microbiome can send signals to your immune cells, which may impact how well and how long CAR T cell therapy will last. We can find out what type of bacteria are in your gut microbiome by studying your stool. We can understand more about the signals sent to the immune system by studying your blood. We will ask for stool and blood at the same time points throughout your treatment. We will study the identities and function of the bacteria and immune cells to understand more about how these signals work during CAR T cell treatment.

To create digital tools to support young adult cancer survivors completing active treatment and transitioning into survivorship care.

The purpose of this study is to create a registry that will collect clinical data from participants attending UNC Hospitals who may present with metastatic cancer and are evaluated to receive radiation therapy. We hope to create a registry that future studies can pull from to study the impacts of radiation therapy on patient cancer outcomes.

The purpose of this study is to identify specific barriers to preventing a late stage cancer diagnosis within communities identified in North Carolina as having a higher rate of advanced cancer diagnoses.

The purpose of the study is to address the lack of sufficient observational data related to lymphoma in Malawi and therefore by doing this to serve as a foundation for developing optimal treatment strategies that would be of more benefits in the treatment of Children, Adolescent and young adults with Burkitt lymphoma.