In this study, we want to learn more about mental health stigma and mental health history. We also would like to learn about how these factors affect a person's willingness to participate in therapy.

To find the safest and most tolerable dose of CAR.B7-H3 T cells to administer in patients with relapsed/refractory platinum-resistant epithelial ovarian cancer.

Immune checkpoint inhibitors (ICIs) are a type of cancer treatment that work by over-activating the immune system to find and kill cancer cells. This type of treatment can sometimes lead to side effects that look like autoimmune diseases (diseases where the immune system attacks the body). We want to collects samples and clinical data from cancer patients taking ICI therapy to understand why some patients get side effects and others don't.

The purpose of the SUNBEAM study is to learn more about factors that put babies and toddlers at higher risk for developing food allergies and eczema. This is an observational study, where we will follow pregnant mothers and their babies from birth to 3 years to learn more about how allergies develop. We are doing this research because there are currently no reliable ways to predict which children will develop food allergies.

We are researching the genetics of those who have major depressive disorder or bipolar disorder and have received or been evaluated for interventional treatments such as ECT (Electroconvulsive Therapy), TMS (transcranial magnetic stimulation), esketamine, and ketamine. "GenECT" is a research study to find ways to improve treatment for severe depression. We want to answer questions like: "Why do some people get severe depression and other people do not?" "Why do interventional treatments like ECT benefit some people more than others?" The GenECT study is a global effort to understand the genetics of severe depression. Dozens of doctors and scientists from around the world are working together with tens of thousands of patients to find out the answers to these questions. UNC is a lead site in this global effort.

Are you a healthy person? Have you wanted to get involved in clinical research in lung diseases? If so, you can join our registry list of interested individuals through a quick online form. We will give you a call if there are studies that you may be eligible for.

To collect cells from the nose and blood of humans to perform various experiments

Do you have mantle cell lymphoma or other non-Hodgkin lymphoma that has either come back or did not get better with your last treatment? If so, you may be able to take part in a study that will modify your own immune cells to see if it may treat your cancer.

Much of autism research has been conducted with males. We want to learn more about the experiences of females with autism and their families. This research will help us to tailor future research studies toward autistic females.

Have you been diagnosed with primary central nervous system (CNS) lymphoma? If so you may be able to take part in a research study looking at whether using the study drugs lenalidomide, and nivolumab can be safely used in addition to the standard treatment of primary CNS lymphoma, and which dose is the most adequate when they are used together.