The purpose of this study is to understand how your gut plays a role in how well CAR T cell therapy works. Your gut is home to bacteria, which we call the gut microbiome. The gut microbiome can send signals to your immune cells, which may impact how well and how long CAR T cell therapy will last. We can find out what type of bacteria are in your gut microbiome by studying your stool. We can understand more about the signals sent to the immune system by studying your blood. We will ask for stool and blood at the same time points throughout your treatment. We will study the identities and function of the bacteria and immune cells to understand more about how these signals work during CAR T cell treatment.
The primary objective of this repository is to make blood samples available for research studies related to histocompatibility and HC transplantation or other cellular therapy.
Screening tool to collect broader demographic and clinical data. Enhance understanding of site specific and trial specific accrual barriers.
The purpose of this study is to learn how having specific help over a period of time (financial navigation) can help reduce your distress related to the cost of cancer. You will complete a survey to see if you have financial distress. If you have financial distress, you will then fill out a few more surveys and be asked more details about your current financial situation to determine what programs could be helpful for you. The surveys can be completed in person, by email, or over the phone. The navigator can help you complete the surveys if needed. After that, depending on your needs, you will have 1-6 appointments with the financial navigator over a period of 2 weeks -4 months. Risks to you are small due to the educational nature of this study. They may include mild emotional distress while talking about your cancer and financial experiences. Benefits
This study is an access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) in pediatric and adult patients with hematologic malignancies and other indications. This protocol will allow access to cord blood units that are unlicensed.
To assess the safety of nonconforming lisocabtagene maraleucel in patients
This is a research study to compare quality of life (QOL) and physical function impairment among breast cancer and lymphoma survivors in Malawi to age- and sex-matched controls, using the PROMIS survey and objective performance-based measures.
This study wants to learn how people with cancer manage their day-to-day health and treatment while receiving medicines for cancer. We will ask patients about their experiences through short surveys and interviews to understand what helps them stay well and avoid emergency visits or hospital stays. The goal is to find ways to better support patients during treatment, especially those who live farther from the hospital or have fewer resources.