The primary objective of the study is to evaluate the safety and feasibility of treating patients with a history of iTTP with efgartigimod, an FcRn inhibitor that reduces IgG autoantibodies, including those responsible for ADAMTS13 depletion.

Gather detailed information on the health and treatment of patients with severe asthma worldwide, track how well patients are responding to treatment, and undertake medical research using data from the registry to improve asthma treatment and care.

This study compares two different surgical tubes and post-op ointments as treatment for one type of glaucoma, an ocular disorder in which the pressure inside the eye is too high.

This study is testing a medication called ziltivekmab to see if it can help people with heart failure.

This study aims to understand how the cities of Durham and of Chapel Hill have changed over time. It seeks to engage neighborhood level change and gain insight into placemaking and engagement with planning processes on a local level.

The purpose of this study is to test a resilience program compared to a physical activity program on change in early childhood education staff's mental health and well-being.

This study will gather feedback from state agency staff and summer meals sponsors on a Summer Meals Site Placement tool.

The purpose is to evaluate coagulation activation and the impact of iron status in patients with Hereditary Hemorrhagic Telangiectasia (HHT). Participants on this study will include patients with HHT, patients with iron deficiency +/- anemia but without HHT, and healthy volunteers The study team will procure single and/or serial blood samples from participants and assess various markers of hemostasis and activation of coagulation, and host iron status.

The purpose of this study is to examine clinical approaches to chronic pain among different medical specialties, types of chronic pain, and patient populations.

The purpose of the study is to capture the time course of patient-reported improvement with VDZ or UST from baseline to Week 52 (end of study).