We will interview researchers whose work involves the science of gene editing or policy implications of human gene editing. We will also conduct observations at conferences and other public meetings. The interviews and observations will document researchers' perspectives on the scientific prospects for applying human gene editing to the prevention of disease, enhancement concerns that might be generated, and views on the appropriate governance of human genome editing research.

This is a research study to evaluate the comparative effectiveness and tolerability of outpatient transrectal prostate biopsy versus transperineal prostate biopsy, both MRI-targeted.

I will interview members of wind bands to understand their distinct qualities in U.S. musical diplomacy efforts during the Cold War and their repercussions today.

The purpose of this research study is to better understand the characteristics and workforce of school-based behavioral health (SBBH) programs across the U.S. in order to identify the resources needed to expand these services.

• To provide investigators in the Division of Gastroenterology with the sources of clinical information for basic research and clinical studies of inflammatory bowel diseases. • To provide optimal and standardized collection of stool for such studies.

We aim to develop, field-test, and promote improved ways to measure and assess the public health hazards associated with sanitation systems and practices in sub-Saharan Africa, with the overall goal of informing sanitation planning and implementation at community levels. This will involve learning more about the range and distribution of sanitation technologies encountered in two cities of Africa (i.e., Kampala and Lusaka). Learning more about the levels of microbiological hazard in onsite sanitation systems especially septic tanks and other technology-specific lessons can be usefully incorporated in citywide sanitation improvement tools.

To assess patient satisfaction with a Clinical Pharmacist Practitioner (CPP) provider for their mental healthcare

The purpose of this research study is to follow new parents with cystic fibrosis for 5 years to learn more about how their health changes when they become parents. The information we gather in this study will be used to inform future interventions to help people with CF successfully prepare for and transition into parenthood

To develop an artificial intelligence (AI) and machine learning (ML) process focused on physicians' variability during the pre-treatment peer review processes and assess the impact of the process in the RT work system on patient safety.

Predictive modeling has recently attracted a lot of attention from organizations trying to leverage AI and big data to improve their work processes such as decision-making. However, real-world problems are rarely well-formulated machine learning problems. Practitioners have to supply a well-defined predictive target to operationalize a predictive model. In such cases, they often resort to using observed variables to approximate the actual construct of interest. For example, people have used high sales numbers as a proxy for a good employee. Proxy label selection is a recurring challenge when predictive ML is applied to real-world problems. The purpose of this interview study is to understand how ML practitioners select proxy labels, evaluate proxy labels, and iterate through the different tasks involved.