The purpose of the HEALEY ALS Platform Trial is to develop and administer various clinical trials under different regimens with ALS to provide multiple treatment options for patients with ALS.

To determine if individuals with chronic ankle instability (CAI) improve walking gait characteristics (ie step length and width) following two single session interventions that manipulate visual information available while walking.

The goal of this study is to better understand the organizational factors that influence burnout, clinician well-being, and patient outcomes. We hope to identify practices that can support ICU teams to provide high-quality care.

The purpose of this study is to meet with elementary school homeroom teachers and middle school social science teachers within the district of Salihli-Turkey and document their knowledge and perceptions regarding the archaeological site of Sardis, archaeology, and archaeologists. The long-term goal of this research is to utilize the data collected to establish a foundation for the development of teacher training programs on archaeological site of Sardis, break teachers' prejudices against the discipline of archaeology, and foster a sense of trust towards international archaeologists actively excavating in this area.

Osteosarcoma is the most common primary bone malignancy of childhood and adolescence. Survival rates for patients with standard risk (localized, resectable primary tumors) and high-risk disease (presence of metastases, unresectable or primary pelvic tumors) are 70% and 20-30%, respectively, and have remained unchanged for several decades despite numerous attempts to augment standard therapies. Multi-targeted receptor tyrosine kinase inhibitors (MTKIs), such as cabozantinib, can target signaling pathways that are known to be altered in osteosarcoma. Several MTKIs including cabozantinib have recently shown clinical evidence of activity in prospective studies for both pediatric and adult patients with advanced osteosarcoma. Furthermore, feasibility of administering MTKIs in combination with cytotoxic chemotherapy has previously been shown in patients with AML, hepatocellular carcinoma, and soft tissue sarcomas. Osteosarcoma is the most common primary bone malignancy of childhood and adolescence. Survival rates for patients with standard risk (localized, resectable primary tumors) and high-risk disease (presence of metastases, unresectable or primary pelvic tumors) are 70% and 20-30%, respectively, and have remained unchanged for several decades

The purpose of this research study addresses the need to understand how higher levels of education among gay men impact people's perception of gay men as leaders.

We want to create a registry of new and established patients with Keratoconus who attend the UNC Department of Ophthalmology, with the aim of understanding risk factors, how the disease develops and response to treatment.

he purpose of this study is to explore how healthcare professionals, including doctors, psychologists, and nurses, are using new technologies called Generative AI in their daily work. Generative AI tools, such as systems that help write clinical notes or summarize conversations, have the potential to save time and make tasks easier for healthcare providers. This study will ask participants to share their experiences with these tools, including what they find helpful, any challenges they've faced, and suggestions for improvement. By gathering this information, we hope to better understand how these tools are currently being used and how they can be improved to help healthcare professionals provide better care to their patients. The results of this study will be used to guide future improvements to Generative AI tools and offer practical advice for clinicians who are considering using these technologies in their own practices.

This project tests a short, evidence-based video to help educate patients about effective and safe pharmacologic and non-pharmacologic therapies for acute musculoskeletal pain (MSP). Subjects will be randomly placed into one of two study groups: intervention (educational video) and usual care. Patients will be contacted at baseline and at 1 and 3 months after the date of their acute visit encounter for follow-up. The primary aim of this study is to evaluate the success of the video intervention for improving pain recovery and preventing long-term opioid use among adults with musculoskeletal pain.

The purpose of this research study is to evaluate and understand the latest advancements in histone modification analysis techniques and their applications.