A multi-center open-label trial evaluating the efficacy and safety of daratumumab in treatment of patients with proliferative glomerulonephritis with monoclonal immunoglobulin deposits.

To determine whether newly-developed naloxone training materials increase how often pharmacists dispense naloxone.

This is a multicenter, open-label study to study the safety and characteristics of DNL310, an investigational drug designed to treat both the body and brain manifestations of Mucopolysaccharidosis type II (MPS II; Hunter syndrome). The plan is for each participant to start at a low dose and increase over time until a final dose is achieved. Blood, urine and CSF samples will be taken, and tests and assessments will be done to see how your child is doing in the study.

This study focuses on how communities near the coast deal with frequent but shallow flooding. We focus on small towns in Carteret County, NC, where families have lived for a long time. We want to talk to residents here to understand how they see their quality of life changing as flooding increases. We also want to see if their tolerance for this type of flooding changes depending on how bad it is and which areas are affected. By talking to residents and modeling flooding, we hope to characterize how livable this place may be in the future considering these floods.

In order to improve the biomedical research environment at UNC-Chapel Hill, we are developing new training opportunities and evaluating how well they work

To better understand the impact of UNC's Bridge the Gap program.

This study will help us learn more about how strongly our Triple P professional networks, both individual and organizational, in North Carolina and South Carolina are connected. We'll use this information to help create or sustain network connections to promote effective implementation of the Triple P Positive Parenting Program.

This study will explore the ways that anti-racism education via an analysis of structural racism and white race caucusing influence what white people do to navigate structural racism as it presents in the everyday.

This study will investigate two different systems to help analysts enter operator comments (i.e., annotations) on transcripts of audio conversations.

The purpose of this research study is to assess how inflammatory bowel disease (IBD) influences reproductive and contraceptive concerns for young women with IBD and to explore their preferences regarding contraceptive counseling in the IBD clinic. The results from this study will give providers essential insight into the contraceptive use concerns and preferences of young women with IBD.