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EVOLVE Study: Understanding risk for depression in the pubertal transition

Girls are almost 3 times more likely to develop mood disorders after the onset of puberty relative to males. This profound gender disparity suggests a critical role of ovarian hormones (such as estrogen) in the emergence of adolescent mood disorders. The purpose of the EVOLVE study is to learn about the effect of estrogen variation and stress in promoting mood symptoms during the pubertal transition.

Age & Gender

  • 11 years ~ 14 years
  • Female, Gender Inclusive

Contact the Team

Location

Thank you for your interest, but this study is not currently enrolling.

North Carolina (Chatham, Durham, Orange, Wake)

Additional Study Information

Principal Investigator

Elizabeth Andersen
Psychiatry - Research

Study Type

Behavioral or Social
Observational

Study Topics

Behavior
Brain, Head, Nervous System
Child and Teen Health
Developmental
Glands and Hormones
Healthy Volunteer or General Population
LGBTQIA+
Mental and Emotional Health
Minority Health
Parents of Children
Sexual and/or Reproductive Health
Sleep
Women's Health

IRB Number

20-2816

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