Mechanism of sickle cell disease-specific venous thromboembolism

The purpose of this research study is to evaluate the effects of Sickle Cell Disease on the state of coagulation and effects on generation of certain coagulation proteins. People with sickle cell disease tend to have a higher rate of thrombosis which is not fully understood. Through this study, we hope to gain a better understanding of the effects of sickle cell disease on turning on coagulation that ultimately leads to a thrombotic event.