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Radiation, PARP inhibition, and immunotherapy for breast cancer brain metastasis

The purpose of this research study is to see if adding the PARP inhibitor olaparib concurrently with SRS followed by immunotherapy (durvalumab) and chemotherapy will lead to better control of breast cancer that has spread to the brain better than the standard approach.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive

Contact the Team

Location

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Florida, New York, North Carolina (Statewide), Ohio

Additional Study Information

Principal Investigator

Colette Shen
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Brain, Head, Nervous System
Cancer (Brain and Other Nervous System, Breast)

IRB Number

20-2970

ClinicalTrials.gov

NCT04711824

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