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Non-invasive brain stimulation for Parkinson's non-motor symptoms

In this study, we want to understand whether we can use non-invasive brain stimulation to treat non-moto symptoms like autonomic nervous system dysfunction and depression in people with Parkinson's disease.

Age & Gender

  • 50 years ~ 90 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide), South Carolina, Virginia

What will be asked of you

At each visit, you will be asked to fill out questionnaires about non-motor symptoms you may be experiencing. You will also have 3 sessions of non-invasive brain stimulation using transcranial magnetic stimulation (TMS), which is a safe and FDA-approved treatment for depression. Each session will be separated by 3 weeks. You will have a brief EEG performed just before and just after each stimulation session. Finally, a member of our study team will call you and ask questions about your symptoms 1 day and 4 days after each stimulation session.

Incentives

Up to $100

In-person visits:
3-4
Phone or online visits:
6
Total length of participation:
2 month

Looking for Specific Volunteers

Able to participate:

  • You have had Parkinson's disease for at least 3 years
  • You are 50-90 years old

Not eligible if:

  • You have a personal history of seizures or epilepsy
  • You have significant cognitive difficulties
  • You take medications to lower blood pressure
  • You have had brain surgery
  • You have severe or poorly controlled medical conditions such as heart failure, diabetes, or kidney failure

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Dawson Hall Building (Vilcom Center)
77 Vilcom Center Dr, Chapel Hill, NC 27514, USA

Secondary Visit Location

Adult Neurology Outpatient Clinic
UNC Meadowmont
300 Meadowmont Village Cir, Chapel Hill, NC 27517, USA

Additional Study Information

Principal Investigator

Miriam Sklerov
Neurology

Study Type

Clinical or Medical
Interventional

Study Topics

Aging
Blood Pressure
Brain, Head, Nervous System
Chronic Conditions
Mental and Emotional Health
Urinary and Bladder
Movement

IRB Number

21-0751

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