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Biomarker for cervical cancer screening study

To determine if plasma circulating HPV DNA (cHPVDNA) has potential as a non-invasive biomarker for identification and treatment monitoring of cervical intraepithelial neoplasia grades 2-3 by characterizing correlation between plasma cHPVDNA levels and cervical intraepithelial neoplasia grade prior to intervention and after excision.

Age & Gender

  • 18 years ~ 99 years
  • Female

Visit Availability

  • Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

You will be asked for a cervical swab, DNA testing, blood draws and urine samples. If you undergo treatment for an abnormal area on the cervix, you may be asked for a second blood draw.

Incentives

$30, Gift Card for participation

Total length of participation:
60 months

Looking for Specific Volunteers

Able to participate:

  • • ≥ 18 years of age on day of signing informed consent
  • • No history of previously treated cervical cancer
  • • Subject is willing and able to comply with study procedures based on the judgement of the investigator or protocol designee

Not eligible if:

  • • Women who are pregnant are excluded

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Lineberger Comprehensive Cancer Center
NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Shivani Sud
Radiation Oncology - Chapel Hill

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Cervical)
Immune System/Infections
Sexual and/or Reproductive Health
Women's Health

IRB Number

19-2196

ClinicalTrials.gov

NCT04274465

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