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Perimenopause Transition Study

The UNC Center for Women's Mood Disorders wants to learn more about mood and brain function during the menopause transition. During this big life change, many women feel and behave differently because of the changes that are happening inside their bodies. We want to find ways to help women feel better during this time. We also want to help them understand the reasons for the strong emotions and different thoughts they might be having.

Age & Gender

44 years ~ 55 years
Female

Visit Availability

Standard business hours (M-F, 8-5)
Extended hours (M-F, early morning or evening)
Weekend hours, if needed
In-home visits available

Location

North Carolina (Chatham, Durham, Orange, Wake)

What will be asked of you

The PEEPs study involved up to 7 visits over about 1 month, but most of the visits can be done on Zoom. We will ask you to take a form of estrogen for three weeks, sit for 2 scans of your brain, and speak regularly with our study team about your thoughts and feelings.

Incentives

$500 Visa gift card, parking provided, blood work, GYN exam, picture of your brain

In-person visits:
2

Phone or online visits:
up to 5

Total length of participation:
1 month

Looking for Specific Volunteers

Able to participate:

You are perimenopausal (skipping menstrual cycles)
You are feeling less interested in activities, feeling down, off, overwhelmed or disconnected

Not eligible if:

You are on any anti-depressants or anti-anxiety medications
You have GYN conditions (i.e. Polycystic ovarian syndrome, Endometriosis, etc.)
You have Ovarian Cancer or Breast Cancer
You have Liver Disease, Kidney Disease, Heart Disease
You have had a stroke

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Marsico Hall (UNC-Chapel Hill)
125 Mason Farm Rd, Chapel Hill, NC 27514, USA

Secondary Visit Location

NC Memorial Hospital
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Gabriel Dichter
Psychiatry - General

Study Type

Clinical or Medical
Interventional

Study Topics

Brain, Head, Nervous System
Mental and Emotional Health
Women's Health

IRB Number

21-2230

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