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THC Vaping Study

In this study, we want to look at the health effects on people who vape CBD or hemp-derived THC, such as Delta8-THC or Delta10-THC. In these vaping liquids, metals, terpenes, pesticides, and microbial products have been identified. The purpose of this research study is to study chemical exposures and biological changes within the airways of THC vapers compared to non-users.

Age & Gender

  • 21 years ~ 40 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

THC users will participate over 4-6 weeks. There will be two in-person visits. This study entails blood, urine, and nasal epithelial lining fluid (NELF) collection at our facility. While also collecting your own NELF samples at home with provided kits. The last part of this study is your responsibility to document your THC use in a provided journal daily. Non-users will complete a single study that entails blood, urine, and nasal epithelial lining fluid (NELF) collection at our facility. Each in-person visit will last approximately 1-1.5 hours.

Incentives

Up to $220 for THC users & 75$ for Non-users

In-person visits:
2
Phone or online visits:
7
Total length of participation:
1-2 months

Looking for Specific Volunteers

Able to participate:

  • You use a THC vaping device

Not eligible if:

  • Recent sinonasal surgery
  • Current use of intranasal corticosteroids (ICS)
  • History of any immunosuppressive disease
  • Nicotine Use

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • Do not use any THC or nicotine products, including other routes of exposure (edibles, nicotine pouches, etc.)

Not eligible if:

  • Recent sinonasal surgery
  • Current use of intranasal corticosteroids (ICS)
  • History of any immunosuppressive disease
  • Nicotine Use

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Center for Environmenal Medicine, Asthma and Lung Biology (CEMALB)
U.S. EPA Human Studies Facility (UNC-Chapel Hill)
104 Mason Farm Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Ilona Jaspers
Pediatrics - Allergy Immunology and Rheumatology

Study Type

Clinical or Medical
Observational

Study Topics

Lungs and Breathing

IRB Number

23-1608

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