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Type 2 Diabetes Blood Sugar Control and Weight Loss Study

A research study to test the effect of a new investigational drug for people with type 2 diabetes on once-daily basal insulin with or without metformin.

Age & Gender

18 years ~ 99 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

You will need to self-inject study medication once weekly, attend 7 of the visits fasting, and complete questionnaires using a questionnaire app. You will need to communicate with the study team weekly to adjust your insulin doses. You will need to record information about your study medicine doses, your insulin doses, and your blood sugars using an eDiary and provided blood glucose meter. You will also need to use a highly effective method of contraception if you are of childbearing potential.

Incentives

Information provided upon request

In-person visits:
11

Phone or online visits:
33

Total length of participation:
1 year

Looking for Specific Volunteers

Able to participate:

You were diagnosed with type 2 diabetes at least 180 days before your first study appointment
You are on a stable once-daily dose of basal insulin alone or in combination with metformin
Your HbA1c is between 7-10.5%
Your BMI is ≥ 25 kg/m2

Not eligible if:

You are pregnant, breast-feeding, intend to become pregnant during the study period, or are unwilling to use highly effective contraception
You have used any medication for diabetes other than basal insulin or metformin in the last 90 days
You have recurrent severe hypoglycemic episodes or hypoglycemia unawareness
You have had a weight loss procedure that has not been reversed, or have used any weight loss medications in the last 90 days
You have other unstable or critical chronic illnesses

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical Research Unit
UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Tahereh Ghorbani Rodriguez
Medicine-Endocrinology

Study Type

Clinical or Medical
Interventional

Study Topics

Diabetes

IRB Number

24-0140

ClinicalTrials.gov

NCT06323161

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH. This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

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Questions?

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