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Depression Study Medication Trial

The purpose of this study is to understand if a new oral medication (pill) can be used to treat depression in people who have not felt relief from other anti-depression medications.

Age & Gender

  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

You will be asked to come in for a screening visit to find out if you are eligible to participate. If you are able to participate, you will take a study medication daily for 4 weeks, and you will be asked to come to the clinic each week for a visit. After you finish the medication, you will be asked to come in for two additional follow-up visits 1 and 2 weeks after you finish the medication. During the clinic visits, you will be asked questions about how you are feeling. We will also have a blood draw at each visit and have your heart activity measured by an ECG.

Incentives

$100 per visit completed, up to $800

In-person visits:
8
Total length of participation:
About 6 weeks

Looking for Specific Volunteers

Able to participate:

  • you have depression

Not eligible if:

  • you are pregnant, breastfeeding or less then 6 months postpartum

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Samantha Meltzer-Brody
Psychiatry - General

Study Type

Clinical or Medical
Interventional

Study Topics

Behavior
Mental and Emotional Health
Women's Health
Men's Health

IRB Number

24-0253

ClinicalTrials.gov

NCT06254612

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