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Adults with Blood Cancer

to see how well the therapy of AK117/placebo combined with Azacitidine fights Higher-risk Myelodysplastic Syndrome and how safe it is.

Age & Gender

  • 18 years ~ 99 years
  • Male, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

United States (Nationwide)

What will be asked of you

If you decide to take part, you will receive medication given by blood via a vein every two weeks. Azacitidine will be given under the skin/subcutaneously. At each visit you will be asked questions about your health and medications you are taking. You will also answer questionnaires. Blood draws for routine tests should be expected at every visit on site. You will also have to give samples of salvia, or bone marrow, physical exam, chest

Incentives

In-person visits:
18+
Phone or online visits:
20+
Total length of participation:
24 Months

Looking for Specific Volunteers

Able to participate:

  • >18 years of age
  • Good Kidney function
  • Newly diagnosed Blood Cancer
  • Able to have bone marrow sample collection
  • Good Venous access

Not eligible if:

  • Prior Chemotherapy treatment
  • History of Anemia
  • Major surgery in past 4 weeks
  • Current Hypertension
  • Active Infection

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Joshua Zeidner
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Leukemia)

IRB Number

24-0365

ClinicalTrials.gov

NCT06196203

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