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Akero 105

We are studying an investigational drug, Efruxifermin, to see if it will help in the treatment of liver inflammation and scarring (fibrosis) in adults diagnosed with NASH (non-alcoholic steatohepatitis) and MASH (metabolic dysfunction-associated steatohepatitis).

Age & Gender

  • 18 years ~ 80 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

At each visit, we will collect your vials, and blood, and ask you questions about your health since the last visit. You will also learn how to self-inject the study medication (taken subcutaneously in your arm, thigh, or belly). You may be asked to have a liver biopsy done if you do not have one previously and we'll take scans of your liver to monitor throughout the study.

Incentives

Information provided upon request

In-person visits:
24
Total length of participation:
About 2.5 years

Looking for Specific Volunteers

Able to participate:

  • You have been diagnosed with non-alcoholic steatohepatitis (NASH)/metabolic dysfunction-associated steatohepatitis (MASH)

Not eligible if:

  • You have a history of liver cirrhosis

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Visit Study Website

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

A Barritt
Medicine-Gastroenterology

Study Type

Clinical or Medical
Interventional

Study Topics

Kidneys and Liver

IRB Number

24-0469

ClinicalTrials.gov

Not yet available

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