The purpose of this research study is to compare the effectiveness of two combinations of anticancer study drugs in treating your Chronic Lymphocytic Leukemia (CLL). The first combination is sonrotoclax (also known as BGB-11417) and zanubrutinib, while the second combination is venetoclax and obinutuzumab. The aim is to determine which combination of study drugs is more effective in controlling your specific type of cancer,
This study aims to treat your cancer and closely resembles routine care that would be received regardless of participating on a research study. To participate on the study, you will frequently meet with a member of the study team in addition to your oncology care team. The study involves: • Assessments and tests: Measurement of your height, weight, and vital signs (blood pressure, pulse, and temperature); Complete physical examination, Blood sample collection; pregnancy blood test (if applicable); Electrocardiograms (ECG); An echocardiogram (ECHO), multigated acquisition scan (MUGA) or gated heart pool scan (GHPS) scan to check your heart function; Computerized tomography (CT) scan(s) to assess your CLL disease; bone marrow biopsies • Study medications; questionnaires.
study medication, procedure...
NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA
Deborah Stephens
Medicine-Hematology
Clinical or Medical
Interventional
Blood Conditions
Cancer (Leukemia, Lymphoma)
24-0196