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How does the way sugar enters the body affect brain glucose?

We are conducting a research study to understand how different ways of taking sugar into the body change how much sugar gets into the brain. This information may be helpful to get learn about obesity, type 2 diabetes, and neurodegenerative diseases (e.g. Alzheimer's Disease).

Age & Gender

18 years ~ 45 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

Each participant in this study will receive: a physical exam, blood work, IV glucose (sugar) infusion, oral glucose drink (sugary drink), and an MRI scan.

Incentives

Up to $425

In-person visits:
3

Total length of participation:
3 months

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

you are healthy
you are of normal weight (BMI<25)
you do not take any prescription medications

Not eligible if:

you have a known chronic disease
you take any prescription medications besides levothyroxine
you smoke tobacco or engage in high risk alcohol or illegal drug use
you are pregnant, seeking pregnancy, or breastfeeding
you are unable to enter an MRI (claustrophobic or have pacemaker/metal objects inside your body that are not MRI safe)

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

Biomedical Research Imaging Center
Marsico Hall (UNC-Chapel Hill)
125 Mason Farm Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Brooke Matson
Medicine-Endocrinology

Study Type

Clinical or Medical
Observational

Study Topics

Brain, Head, Nervous System
Stomach, Digestion and Gut Health
Eating, Nutrition, and Metabolism
Glands and Hormones
Healthy Volunteer or General Population

IRB Number

24-1476

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH. This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

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Questions?

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