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Tailoring Therapy in Post-surgical Patients with Low-risk Endometrial Cancer

The purpose of this study is to find out if based on a laboratory assessment of the tumour tissue and extent of disease spread, receiving less treatment after surgery is feasible and leads to a low rate of cancer returning for early-stage endometrial cancer.

Age & Gender

18 years ~ 99 years
Female

Visit Availability

Standard business hours (M-F, 8-5)
Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

This study aims to treat your cancer and closely resembles routine care that would be received regardless of participating on a research study. To participate on the study, you will frequently meet with a member of the study team in addition to your oncology care team. The study involves Chest X-rays, CT scans, genetic testing, tissue collections, Radiation therapy treatment, and completion of questionnaires.

In-person visits:
up to 10

Total length of participation:
up to 3 years

Looking for Specific Volunteers

Able to participate:

you have had surgery consisting of hysterectomy and bilateral salpingo-oophorectomy
You have Stage I to III endometrial carcinoma which can be iendometrioid, serous, clear cell, un/dedifferentiated, carcinosarcoma or mixed
You are able and willng to complete the study questionnaires

Not eligible if:

you had prior Neoadjuvant chemotherapy for current endometrial cancer diagnosis
you had prior pelvic radiation
you have a history of other malignancies
you have clinical evidence of distant metastasis

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Lineberger Clinical Research
cancerclinicaltrials@med.unc.edu
(919) 966-4432

Primary Visit Location

Lineberger Comprehensive Cancer Center
NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Olivia Lara
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Uterine (endometrial))

IRB Number

24-1437

ClinicalTrials.gov

NCT05640999

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Questions?

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