HIV-Associated Lung Disease: The Role of Nasal Mucosal Immunity and Microbiome

Some people living with HIV can have chronic lung and breathing issues. We want to learn if the immune system of the nose may lead to these problems. We will collect a sample from the nose using a small strip of paper put in the nose for two minutes. This sample will be tested for inflammation and bacteria. We will do this test in 150 people with HIV and 100 without HIV. We will ask 100 people to come back in 6 months to do the sample again.