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Training Brain-Muscle Communication

We are studying how the brain and muscles work together during simple hand grip exercises. By using special tools to measure brain and muscle activity, we hope to learn how giving people feedback on their body's signals can improve their muscle control. This research could help develop better treatments for people with movement problems caused by conditions like stroke.

Age & Gender

  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)
  • Extended hours (M-F, early morning or evening)
  • Weekend hours, if needed

Location

North Carolina (Statewide)

What will be asked of you

As a participant in this study, you will be asked to attend a single visit lasting about 3 hours. During this visit, you will: Perform simple hand grip exercises using a handheld device. Wear a non-invasive cap to measure your brain activity (EEG) and small sensors to measure muscle activity (EMG). Receive feedback on your brain-muscle communication during the exercises. Undergo a safe procedure called Transcranial Magnetic Stimulation (TMS) to assess how your brain and muscles are connected. There are no invasive procedures, and you'll have rest breaks throughout the session. Your participation will help us better understand how brain-muscle communication works, potentially leading to new treatments for movement disorders.

Incentives

Up to $105

In-person visits:
1
Total length of participation:
3 hours

Looking for Healthy Volunteers

Requirements for healthy volunteers are different than for those with a specific condition. If you are interested in becoming a healthy volunteer for this study, use the below categories to determine if you are able to participate.

Able to participate:

  • You are 18 years of age or older
  • You are right-handed
  • You are neurologically healthy (no history of seizures, brain injuries, or neurological disorders).
  • You do not have any metal implants in your head.
  • You are able to perform simple hand grip exercises.

Not eligible if:

  • You have a history of seizures, epilepsy, or other neurological conditions.
  • You are currently pregnant.
  • You have a history of brain injury or concussions.
  • You are left-handed or ambidextrous (this study requires right-handed participants).
  • You have metal implants in your head (e.g., surgical clips, implants).

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Visit Study Website

Primary Visit Location

Bondurant Hall (UNC-Chapel Hill, School of Medicine)
321 S Columbia St, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Jasper Mark
Department of Health Sciences - Physical Therapy

Study Type

Behavioral or Social
Interventional

Study Topics

Behavior
Bones, Joints, Muscles
Brain, Head, Nervous System
Healthy Volunteer or General Population
UNC Students (undergrad, grad, professional)

IRB Number

24-1912

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Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH.  This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

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