If you decide to participate in this study, there are a few key things we'll ask you to do: Study Visits: You'll visit the study site about 7 times over the course of a year. During these visits, we'll check on your health, take blood samples, perform some routine testing on your liver and eyes and ask about any side effects or changes in your medications. Take Study Medication: You'll take either the study drug (denifanstat) or a placebo (a pill with no active ingredient) once a day for 52 weeks. Complete Questionnaires: We'll ask you to fill out surveys and keep track of certain information in an electronic diary (eDiary) to help us understand how the treatment affects your daily life and well-being. Follow-up: After you complete the treatment phase, there will be one follow-up visit about 4 weeks later. We'll guide you through each step and provide regular check-ins to monitor your progress. You can withdraw from the study at any time if you choose to.