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Master Screening and Reassessment Protocol (MSRP) for Tier Advancement in the NCI MyeloMATCH Clinical Trials

This study aims to determine whether using specific biomarker screening tests can improve how patients with blood and bone marrow cancers access clinical trials throughout their treatment. The goal is to see if this approach makes it easier or more effective for patients to join relevant trials, compared to the standard methods currently used.

Age & Gender

18 years ~ 99 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)
Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

This study will use genetic tests, such as bone marrow biopsies and blood tests, that may find changes in genes in your DNA. Based on these tests, you will be matched with a treatment plan after about 3 days. If you receive a match, you will be provided information about the sub-study to help you decide if you want to join it.

In-person visits:
5-24

Total length of participation:
2 years

Looking for Specific Volunteers

Able to participate:

You have acute myeloid leukemia (AML)
You have myelodysplastic syndrome (MDS)
You're over 18 years old
No prior anti-cancer therapy for AML/MDS (Hydroxyurea permitted)

Not eligible if:

Prior or currently in anti-cancer therapy for AML/MDS (not including Hydroxyurea)
You're under 18
You are currently pregnant or breastfeeding

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Lineberger Clinical Research
cancerclinicaltrials@med.unc.edu
(919) 966-4432

Primary Visit Location

NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Joshua Zeidner
LCCC - Clinical Trials

Study Type

Clinical or Medical
Interventional

Study Topics

Cancer (Leukemia)

IRB Number

24-2431

ClinicalTrials.gov

NCT05564390

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