The purpose of this study is to find out if an investigational treatment called P-BCMA-ALLO1 is safe and will help treat people with Multiple Myeloma. The study is also being done to determine what dose is safe and effective to treat Multiple Myeloma.
In order to enter the study, you have to provide written consent to participate. Then you will undergo screening tests to determine if your cancer has the right characteristics and you are healthy enough to partake in the study. This is called a screening visit. Once you have passed the screening tests and enroll in the study, depending on which treatment you will receive, you may begin a conditioning regimen of chemotherapy or antibody therapy to prepare your body to receive the study drug. The study drug will be given to you after the conditioning chemotherapy or antibody therapy (if given) via an intravenous (IV) infusion. You will then be assessed to see the effects of the study drug treatment. Based on cohort and study arm, you may be required to be admitted to the hospital when you get the study drug and will stay in the hospital for 7 days afterward so the study doctor can watch you closely for any side effects. You will return to your study doctor for regular post-treatment follow up visits after your last study drug infusion. Follow up for this study could last up to 15 years.
NC Cancer Hospital (Basnight)
UNC Hospitals / UNC Medical Center
101 Manning Dr, Chapel Hill, NC 27514, USA
Eben Lichtman
LCCC - Clinical Trials
Clinical or Medical
Interventional
Cancer (Multiple Myeloma)
24-3158