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ARGX-117-2302- Phase 3, Randomized, Double-Blind study to evaluate effectiveness and safety of empasiprubart versus IVIg in patients with multifocal motor neuropathy

Study aims to demonstrate the effectiveness and safety of empasiprubart compared to IVIg in improving functional ability, muscle strength and motor function in patients diagnosed with multifocal motor neuropathy.

Age & Gender

  • 18 years ~ 99 years
  • Male, Gender Inclusive

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

United States (Nationwide)

What will be asked of you

At each visit participants will undergo muscle testing by the clinician for an objective guage of disease progression (include but not limited to- grip strength, and muscle testing) ; multiple quality of life questionnaires , blodo and urine collection, urine pregnancy test in WOCBP , 12 lead ECG and vital signs, study drug or placebo-IVIg administration

Incentives

Subjects will be reimbursed for travel mileage to assist with on site study visits

In-person visits:
39
Phone or online visits:
5
Total length of participation:
49 months

Looking for Specific Volunteers

Able to participate:

  • definite or probable MMN diagnosis

Not eligible if:

  • Pregnancy or lactation

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Rebecca Traub
Neurology

Study Type

Clinical or Medical
Interventional

Study Topics

Brain, Head, Nervous System

IRB Number

25-0771

ClinicalTrials.gov

NCT06742190

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