Open

Weight Loss Study

This study is being done to see if an investigational medication works better than a placebo (dummy medicine) for weight loss.

Age & Gender

18 years ~ 99 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

At each visit, yoy will meet with a member of the study team and answer questions about your health. You will be asked to inject yourself with study medication weekly, complete diaries, answer questionnaires, work with a registered dietitian, and follow the instructions of the study doctor. The study also involves fasting blood draws and EKGs.

Incentives

Information provided upon request, Study medication, study results

In-person visits:
12-23

Phone or online visits:
10-21

Total length of participation:
About 1 year and 8 months for the main study and an additional about 1 year and 8 months for the extension phase

Looking for Specific Volunteers

Able to participate:

your BMI is at least 30
you would like to lose at least 25% of your body weight
you have tried at least once to lose weight by changing your diet
your weight has been stable for the last 3 months
you are willing to inject yourself with study medication weekly

Not eligible if:

you have been diagnosed with diabetes (type 1 or type 2)
you are currently taking or have taken weight loss medication in the last 3 months
you have had obesity treatment with surgery or a weight loss device, with some exceptions
you are currently pregnant or breastfeeding, or intend to become pregnant in the near future
you are of childbearing potential and are not willing to use highly effective contraception, as outlined by the study protocol

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

John Buse
Medicine-Endocrinology

Study Type

Clinical or Medical
Interventional

Study Topics

Obesity

IRB Number

25-0922

ClinicalTrials.gov

Not yet available

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH. This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

Helpful Links

Questions?

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