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ADEPT

This research study is studying whether a higher dose of aspirin will do a better job of lowering the risk of having another preterm delivery or stillborn baby.

Age & Gender

  • 14 years ~ 99 years
  • Female

Visit Availability

  • Standard business hours (M-F, 8-5)
  • In-home visits available
  • Visits can be combined with regular clinical appointments

Location

North Carolina (Statewide)

What will be asked of you

You will be randomly chosen (like flipping a coin) to take either 81 mg or 162 mg of aspirin each day until 36 weeks of pregnancy. These doses are often given to pregnant women in the U.S., but 162 mg hasn't been studied much. We'll collect information about you and your baby from your medical records during your hospital stay. We might also take a blood sample when you join the study and around 22 weeks of your pregnancy. We'll collect any unused medication at the end of the study or when you have your baby.

Incentives

Earn up to $150

In-person visits:
4-8
Phone or online visits:
up to 4
Total length of participation:
8 months

Looking for Specific Volunteers

Able to participate:

  • you are 14 years or older
  • you are pregnant between 10 and 15 week 6 days
  • you are pregnant with one baby
  • you have had a baby born before 35 weeks before
  • you have had a stillborn baby before

Not eligible if:

  • you are allergic to aspirin
  • you take any anticoagulant medication
  • you have had gastric bypass surgery
  • you have known abnormalities of your uterus (womb) or your baby
  • you have certain medical conditions that put you at increased risk of preterm birth. The research team will discuss these with you.

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

OB/GYN Clinic
UNC Health at Panther Creek
6715 McCrimmon Pkwy, Morrisville, NC 27560, USA

Secondary Contact

Secondary Visit Location

OB/GYN Clinic
UNC Health at Weaver Crossing
1181 Weaver Dairy Rd, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

John Thorp
Obstetrics and Gynecology-General Obstetrics and Gynecology

Study Type

Clinical or Medical
Interventional

Study Topics

Pregnancy

IRB Number

25-1069

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