This study includes 100 patients with early breast cancer who've had surgery. You'll join either the non-Black or Black participant group. Researchers will use your stored tumor tissue from surgery to create a test that detects circulating tumor DNA (ctDNA) in your blood. CtDNA can show if cancer cells remain after treatment. You'll give blood samples (about 3 tablespoons) when you start and roughly every three months for a year. These samples will be tested for ctDNA using Haystack Oncology's new method, a less invasive way to monitor your condition. You might give an extra sample before adjuvant treatment. Neither you nor your doctor will get the ctDNA test results because it's still experimental and not FDA-approved. The study is testing if this method accurately tracks the disease. Your doctor will still monitor you with standard tests. You can have blood drawn at your local clinic. Researchers at UNC-CH will use your stored tumor tissue. You can also choose to donate leftover tissue to a biobank for future research. By participating, you allow researchers to use your stored tissue and blood to study how ctDNA can help monitor and treat breast cancer. Only extra tissue and blood not needed for your care will be used. If your doctor needs to collect samples for your care, they may collect a little extra for this study.