Pleuropulmonary Blastoma (PPB) is a rare lung tumor in young children that can grow in stages from less serious (Type I) to more dangerous (Type III). This study will test how well a drug combo: vincristine, topotecan, and cyclophosphamide (VTC) works for serious types (Type II and III) and help decide which patients with less serious tumors (Type I and Type Ir (regressed) PPB ) need chemotherapy after surgery. Researchers will also study the biology of the tumor to learn more about it.
Thank you for your interest, but this study is recruiting by invitation only.
North Carolina (Statewide)
Thomas Alexander
Pediatrics - Hematology/Oncology
Clinical or Medical
Interventional
Cancer (Lung, Pediatric Cancers)
Rare Diseases
25-1874