• Home
  • Study Details
By physician referral or invitation only

1 Zymfentra (Infliximab-dyyb) REal World Cohort STudy

1. Create a prospective cohort of well-phenotyped adult CD, UC and IBDU patients with serial clinical and patient-reported data collected throughout 12 months of Zymfentra (IFX -dyyb) therapy. 2. To determine clinical response and remission rates, course of stool calprotectin values and persistence of therapy with Zymfentra (IFX -dyyb) for induction and maintenance therapy. 3. Assess the correlation of various outcome measures in CD, UC or IBDU (short Crohn's disease activity index (sCDAI), Simple Clinical Colitis Activity Index (SCCAI), Urgency score, Fatigue,SIBDQ, PROMIS measures for depression, anxiety, and social satisfaction and work productivity and activity impairment. 4. Assess the effect of Zymfentra (IFX-dyyb) on patient reported fistula symptoms in patients with CD with pre-existing perianal fistulizing disease. 5. Assess persistence and need for dose escalation therapy of Zymfentra (IFX-dyyb). 6. Assessment of trough levels taken in the setting of standard of care before and after start of Zymfentra (IFX-dyyb).

Age & Gender

  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive

Contact the Team

Location

Thank you for your interest, but this study is recruiting by invitation only.

North Carolina (Statewide)

Additional Study Information

Principal Investigator

Hans Herfarth
Medicine-Gastroenterology

Study Type

Clinical or Medical
Registry

Study Topics

Stomach, Digestion and Gut Health

IRB Number

25-2184

Research for Me logo

Copyright © 2013-2022 The NC TraCS Institute, the integrated home of the NIH Clinical and Translational Science Awards (CTSA) Program at UNC-CH.  This website is made possible by CTSA Grant UL1TR002489 and the National Center for Advancing Translational Sciences.

Questions?

  • This email address is being protected from spambots. You need JavaScript enabled to view it.
logo for the North Carolina Translational and Clinical Sciences Institute
logo for UNC Health
logo for UNC School of Medicine
logo for UNC Research