Study Details

Open

Kidney Health Study Opportunity

ANCHOR is a research study to see if a new investigational drug, called ABBV-CLS-628, can help people with a kidney condition called Autosomal Dominant Polycystic Kidney Disease (ADPKD). We want to see if this new drug works well for those who have this condition.

Age & Gender

18 years ~ 55 years
Male, Female, Gender Inclusive

Visit Availability

Standard business hours (M-F, 8-5)
Extended hours (M-F, early morning or evening)

Location

North Carolina (Statewide)

What will be asked of you

You'll have a check-up with a doctor. You'll give blood and urine samples. We'll check your blood pressure, height, and weight. We'll also ask about any medications you take. There's a heart test, a hearing test, and a bone scan. We'll do MRI scans of your kidneys and, if needed, a simple pregnancy test. Lastly, you'll answer some easy questions about how you feel in your daily life.

Incentives

You can earn between $50 to $300 for each visit you complete., We will also cover your travel costs if you drive. If you don't have a car, we can help with your travel arrangements.

In-person visits:
28

Phone or online visits:
1

Total length of participation:
2 years and 3 months

Looking for Specific Volunteers

Able to participate:

you have Autosomal Dominant Polycystic Kidney Disease
your kidney function is still good but not perfect (eGFR >30 and < 90)
you are not planning to have a child in the next 2 years and 4 months

Not eligible if:

you are on tolvaptan and want to stay on that drug
you are close to dialysis, on dialysis or post-transplant
you had kidney surgery in the last 6 months
you have type 2 diabetes
you have a metal implant that would make it impossible for you to have an MRI

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Emily Chang
Medicine-Nephrology

Study Type

Clinical or Medical
Interventional

Study Topics

Kidneys and Liver

IRB Number

25-1136

ClinicalTrials.gov

NCT06902558