A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

This study is being conducted to see how well a study drug called ponsegromab works and if it might improve health and quality of life compared to a placebo in adults who have cachexia (a condition causing significant unintentional weight loss and muscle wasting) and metastatic pancreatic cancer, for which they receive initial chemotherapy.