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PIONEER

The purpose of this study is to learn about the effects of a study drug on decreasing the damage to the kidneys and see how safe the study drug is for patients with IgAN/IgAVN, pMN, or MCD/FSGS.

Age & Gender

  • 10 years ~ 80 years
  • Male, Female

Visit Availability

  • Standard business hours (M-F, 8-5)

Location

North Carolina (Statewide)

What will be asked of you

At each visit, you will meet with the study team and fill out questionnaires. You will also complete sample collections including home urine collection and blood draws in the clinic. The study medication will be taken weekly at home except for the days you have a study visit.

Incentives

Amount varies by visit type ranging from $100 to $150 for visits

In-person visits:
11
Total length of participation:
12 Months

Looking for Specific Volunteers

Able to participate:

  • Kidney Diseases including: IgAN/IgAVN, pMN, or MCD/FSGS
  • Protein in the Urine (UPCR >1g/g)
  • eGFR ≥ 20 mL/min/1.73m2

Not eligible if:

  • Do not have the type of kidney disease mentioned above
  • receiving dialysis

Contact the Team

Visit Location

Contact & Visit Location

Primary Contact

Primary Visit Location

Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA

Secondary Visit Location

UNC Eastowne Medical Office Building
100 Eastowne Dr, Chapel Hill, NC 27514, USA

Additional Study Information

Principal Investigator

Amy Mottl
Medicine-Nephrology

Study Type

Clinical or Medical
Interventional

Study Topics

Kidneys and Liver

IRB Number

25-1420

ClinicalTrials.gov

NCT06983028

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