This study will test the safety of a drug called nucresiran and will find out what effects, if any, nucresiran has on people with hereditary transthyretin amyloidosis (hATTR) with polyneuropathy.
Generally, you will go to the study site where you will meet with your study team. They will ask how you have been and perform standard tests that include: ·Asking about your health and any medications or supplements you take. ·Collecting blood and urine samples ·Study drug administration ·Checking your vital signs (like blood pressure, heart rate, respiratory rate, temperature, and weight) ·Neurological exams ·Physical exams ·Questionnaires ·Heart monitoring tests ( electrocardiograms [ECGs], echocardiograms [ECHOs])
Clinical and Translational Research Center (CTRC)
Burnett-Womack Building (UNC-Chapel Hill)
160 Dental Cir, Chapel Hill, NC 27514, USA
Rebecca Traub
Neurology-Neuromuscular
Clinical or Medical
Interventional
Brain, Head, Nervous System
Chronic Conditions
Genetics and Genetic Disorders
25-2866