Developing Resources to Enhance Understanding of CAR-T Therapy for Lupus and Autoimmune Diseases 

Despite the ground-breaking benefits and scientific advancements in Chimeric Antigen Receptor T-cell (CAR-T) cell therapy, there are significant challenges for CAR-T clinical trials in diseases outside of cancer. These barriers include lack of awareness and knowledge, apprehension and hesitation amongst patients and healthcare providers, logistical and financial concerns, and inequitable access to this new therapy. This project aims to address these challenges by developing innovative strategies to enhance access to participation in CAR-T clinical trials in lupus and autoimmune diseases. The insights and strategies developed from this work will be used to inform and advance the reach, relevance, and implementation of innovative strategies to advance opportunity and accessibility for cell-based therapy trials in other disease states, beyond the example of lupus and autoimmune diseases.