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UNC-Chapel Hill Department of Medicine

350 studies match your search
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UNC Pleural Fluid Registry

Have you been diagnosed with pleural fluid, and have been referred for a pleural fluid drainage? If so, you may be able to participate in a research registry to help us learn more about lung cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)

Symptom Monitoring for Patients with Hospital-Diagnosed Advanced Lung Cancer

The purpose of this study is to understand how monitoring symptoms at home after lung cancer diagnosis could impact quality of care and the likelihood of returning to the hospital. This study will also help us understand whether symptom monitoring in patients with advanced lung cancer is helpful for patients and the clinical teams who care for them.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Cancer (Lung)
  • Lungs and Breathing
Open

Mycobacterium Avium Complex (MAC) Lung Disease Treatment Study

Have you been recently diagnosed with Mycobacterium Avium Complex (MAC) lung disease and are looking into options for treatment? You may be able to take part in a trial of a new, oral medication called SPR720. We are doing this study to learn more about both the safety of the medication and how well it works to combat MAC lung disease. Compensation will be provided to all participants who complete the trial.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Immune System/Infections
  • Lungs and Breathing
  • Rare Diseases
Open

How does fat impact brain metabolism?

Fuel for Thought: How do sugar and fat affect each other in the brain? Do you ever wonder what happens in your brain when you eat dessert? And why sugary and fatty foods are so appealing? If so, you may eligible to participate in a research study to understand the impact of sugar and fat on the brain!

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Coming Soon

Ph3 Randomized, Double-blinded, Placebo with Atezolizumab and Bevacizumab

This study is assessing the effectiveness and safety of tiragolumab, an anti-TIGIT monoclonal antibody, when given with atezolizumab and bevacizumab as a first-line treatment for unresectable, locally advanced or metastatic patients with hepatocellular carcinoma (HCC). TIGIT is thought to play an important role in HCC's response to immunotherapy treatments such as atezolizumab. This study will assess whether the addition of tiragolumab to atezolizumab and bevacizumab will improve response and clinical outcomes.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Kidney)
Open

Melanoma Research Study

Have you been diagnosed with high-risk Melanoma skin cancer? Are you now melanoma free after surgery? If so, you may be able to take part in this research study. This study will compare a new combination of drug (Fianlimab and cemiplimab) with another standard drug (pembrolizumab). This will allow the study team to understand the side effects of the treatment, how they work and if they improve the quality of life.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Melanoma)
Open

Osteoarthritis Prevention Study

Did you know that over 250 million persons are affected by Osteoarthritis? It is the leading cause of disability among adults and has no cure. Prevention of OA is preferable to treatment and females are affected at nearly twice the rate as males. If you are a female, at least 50 years of age, overweight, with no or occasional knee pain, you may be able to participate in a research study to find out if a diet and exercise program or a health education program prevent knee OA.

Age & Gender
  • 50 years ~ 99 years
  • Female
Study Interest
  • Aging
  • Healthy Volunteer or General Population
  • Wellness and Lifestyle
  • and 5 more
Open

How do APOE genetic variants impact brain metabolism?

If you are healthy and between the ages of 30-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Age & Gender
  • 30 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Eating, Nutrition, and Metabolism
  • Healthy Volunteer or General Population
  • Obesity
Open

Study of Oral Epetraborole for the Treatment of M. Avium Complex (MAC) Disease

Are you currently diagnosed with an M. Avium Complex (MAC) infection of your lungs? Have the treatments you received not improved your condition? If so, you may be eligible for a research study to learn if a new medication (Epetraborole) is safe and effective in treating this disease. Monetary compensation will be provided to all participants.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Immune System/Infections
  • Lungs and Breathing
  • Microbiome
  • Rare Diseases
Not currently enrolling

Type 1 Diabetes Inhaled Insulin Study

In this study, we want to learn more about the safety and effectiveness of inhaled insulin and continuous glucose monitor (CGM) use compared to usual care for people with type 1 diabetes.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
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