Research Studies

UNC-Chapel Hill Department of Medicine

343 studies match your search
By physician referral or invitation only

Understanding Sickle Cell Trait

This study focuses on individuals with sickle cell trait (SCT) to see if their hemoglobin S levels have any effects on red blood cells, blood clotting, or kidney function.

Age & Gender
  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Healthy Volunteer or General Population
  • Minority Health
Coming Soon

BandPass: A Remote Monitoring System for Strength

The purpose of the study is to evaluate a new device and an 'app' that measures and tracks strength in older adults. We would like older adults to test the system to make sure it is working accurately.

Age & Gender
  • 65 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Chronic Conditions
  • Physical Disability
  • and 3 more
Open

Hydrolyzed Formula in Infants and Children with Cow's Milk Allergy

The purpose of this study is to determine if an extensively broken-down milk protein formula is safe for children with cow's milk protein allergy.

Age & Gender
  • 3 months ~ 12 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
Open

Neutrophil Blood Cell Count Study

Are you Black/African American or have Middle Eastern ancestry? Are you not taking any medicines that could change your blood count? If so, you might be able to join a study to find out the normal levels of a type of blood cell called neutrophils. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • UNC or UNC Health employees
Coming Soon

Advanced Cancer Decisions Study

In this study, we want to learn about a new tool that helps cancer patients make decisions. We also want to understand how patients and doctors communicate when choosing treatments.

Age & Gender
  • 60 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Brain and Other Nervous System, Breast, and 15 more)
Visit Location
Open

ALAMERE - NSI-8226-201

Are you living with eosinophilic esophagitis (EoE)? Consider joining our research study to help advance treatment options for this condition. We invite you to participate in a clinical trial comparing the effects of solrikitug, a potential new medicine, with a placebo. By joining, you'll contribute to understanding the effectiveness and safety of solrikitug in treating EoE. The study aims to evaluate its impact on tissue inflammation, difficulty swallowing, and overall quality of life. Your participation is voluntary, and you can withdraw at any time without losing medical benefits. With approximately 157 participants globally, you'll receive thorough medical monitoring throughout the 72-week study period. Plus, you'll have opportunities to discuss your experience with our team and internationally recognized EoE researcher, Dr. Evan Dellon. Make a difference in EoE research-join us today and be part of the journey towards better treatments for EoE.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
  • Stomach, Digestion and Gut Health
  • Women's Health
  • and 3 more
Not currently enrolling

19F MRI Healthy vs. CF

Researchers are collecting data on lung imaging to evaluate how well a person's lungs are working which will provide additional information about lung disease and how such diseases respond to treatment. The purpose of this study is to evaluate the use of inert (non-reactive) gas mixed with oxygen as contrast agent to image the airway spaces in normal human lungs and the lungs of persons with cystic fibrosis. A contrast agent helps the investigator to see spaces inside your lungs that are normally not visible. These images will be compared with spirometry (a non-imaging measure of global lung function used routinely in the clinic).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • Lungs and Breathing
Coming Soon
Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Kidney)
Not currently enrolling

ICU survivors and Family Support Study

In this study, we want to find ways to help people who have been in the intensive care unit (ICU) and their families. We want to hear about your experiences and thoughts on a new program to help you adjust to life after leaving the ICU.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Lungs and Breathing
  • Mental and Emotional Health
  • Opinions and Perceptions
Visit Location
100% Remote (online, phone, text)
Coming Soon

AIRPanc - Ph2 Randomized Study Evaluating Patients with advanced Pancreatic Ductal Adenocarcinoma

The purpose of this study is to combine standard radiation therapy with drugs that stimulate the body's immune system against cancer cells (by targeting the protein PD-1), while adding drugs which also target the pathway that the tumor uses to evade the immune system (the CD73 and A2a/b pathways).The main goal of this study is to find out if study treatment with zimberelimab (an antibody which binds the protein PD-1) and stereotactic body radiation therapy (SBRT) alone or in combination with quemliclustat (a drug which blocks CD73), with or without etrumadenant (a drug which blocks the A2a/b) given before surgery is safe and if it can further increase the immune response against the tumor.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Pancreatic)
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