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Research Studies

UNC-Chapel Hill Department of Medicine

376 studies match your search
Not currently enrolling

Telehealth Weight Loss Intervention

The purpose of this research study is to identify the best initial treatment for achieving weight loss in older adults aged 65─85 years with obesity and multiple medical conditions. We will also investigate how to adapt the weight loss plan for those who struggle to lose weight after the first two months (8-weeks) of participation

Age & Gender
  • 65 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Behavior
  • Chronic Conditions
  • Obesity
Coming Soon

GI Alpha-Gal study

To investigate and evaluate the differences in Gastrointestinal (GI) allergic symptoms caused by ingestion of alpha-gal-containing and alpha-gal-free pork meat.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
  • Stomach, Digestion and Gut Health
Not currently enrolling

A Study of ZL-1211 in Patients With Advanced Solid Tumor

This study is being done to learn more about the effects of ZL-1211 for treating advanced or metastatic solid tumors. This is the first time that ZL-1211 will be given to humans

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Colorectal)
Open

Nutrition & Dietary Assessment Pilot Study

Our team is exploring how technology can help us capture dietary information. We are looking for older adults who will be willing to help us see what is the most effective way to capture nutritional information.

Age & Gender
  • 65 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Eating, Nutrition, and Metabolism
  • Obesity
  • and 4 more
Visit Location
100% Remote (online, phone, text)

Acute Myeloid Leukemia Study

This is a research study for people diagnosed with AML who are not able to receive intensive chemotherapy. The purpose of this study is to see if adding a third drug (magrolimab) to a combination of two drugs (venetoclax and azacitidine) is more effective than using venetoclax and azacitidine.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
Open

Myelodysplastic Syndrome or Acute Myeloid Leukemia study

Do you have AML or MDS and are not eligible to receive intensive chemotherapy? Are you looking for another treatment option? In this study, we want to see if the study drug, SL-172154, works better alone or in combination azacitidine or with azacitidine and venetoclax.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
Open

Diabetes Control in Dialysis-Dependent Kidney Failure

Do you have type 2 diabetes? Do you have kidney failure and require hemodialysis or peritoneal dialysis? You may be able to take part in a research study to find out if using an approved medication (semaglutide) improves blood sugar control. Study medication and diabetes management provided. Participants will be compensated for their time.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Diabetes
  • Kidneys and Liver
  • Obesity
Open

UNC Pleural Fluid Registry

Have you been diagnosed with pleural fluid, and have been referred for a pleural fluid drainage? If so, you may be able to participate in a research registry to help us learn more about lung cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung)
  • Lungs and Breathing
Visit Location
100% Remote (online, phone, text)
Open

Symptom Monitoring for Patients with Hospital-Diagnosed Advanced Lung Cancer

Do you have advanced lung cancer and are you receiving lung cancer treatment or monitoring at UNC Cancer Hospital? If so, you may be able to take part in a research study to help us understand how monitoring your symptoms at home right after your lung cancer diagnosis could impact your quality of care and the likelihood of returning to the hospital.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Cancer (Lung)
  • Lungs and Breathing
Open

Mycobacterium Avium Complex (MAC) Lung Disease Treatment Study

Have you been recently diagnosed with Mycobacterium Avium Complex (MAC) lung disease and are looking into options for treatment? You may be able to take part in a trial of a new, oral medication called SPR720. We are doing this study to learn more about both the safety of the medication and how well it works to combat MAC lung disease. Compensation will be provided to all participants who complete the trial.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Immune System/Infections
  • Lungs and Breathing
  • Rare Diseases
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