Are you 16 years and older, have Eosinophilic Esophagitis, have tried other therapies but they have not worked, and you have had multiple dilations for narrowing in your throat in the past 12 months? If you meet these criteria then you may be eligible for a study investigating the use of dupilumab to treat EoE patients with severe strictures. Compensation provided.

Can we increase the clinical complete response rate (tumor disappears by exam, endoscopy, and imaging) by adding a 3rd drug (irinotecan) to the standard regimen of FOLFOX or CAPOX given following long-course chemoradiation for patients with locally advanced rectal cancer? We are doing this study because we want to find out if this approach is better or worse than the usual approach for your rectal cancer. The usual approach is defined as care most people get for locally advanced rectal cancer.

Do you have known or suspected lung and/or head and neck cancer? Are you scheduled for a tumor biopsy? If so, you may be able to participate in a research registry aimed at learning more about lung and head/neck cancer.

Are you receiving initial treatment for non-small cell lung cancer or invasive squamous cell carcinoma of the head and neck and want to participate in research that aims to improve treatment and care of future patients with the same diagnosis? If so, you may be able to participate in a study for an investigational blood test to predict whether your cancer will come back.

Have you been diagnosed with Non small cell cancer? If so, you may be able to take part in a research study looking at the combination of durvalumab and platinum doublet chemotherapy (carboplatin/abraxane or carboplatin/pemetrexed) with or without abequolixron (RGX-104) before surgery.

The purpose of this study is to evaluate MEDI5752 alone or in combination with other drugs in adult subjects with advanced solid tumors.

Have you been diagnosed with small cell lung cancer? Is your current treatment no longer working in controlling your cancer? If so, you may be able to take part in a research study looking at giving trilaciclib to help minimize the side effects of lurbinectedin.

Have you been diagnosed with Leukemia and looking for another option? Do you have Chronic Myelogenous Leukemia? In this study, we want to learn more about how effective the study drug (asciminib) works for patients with CML-CP who have had one prior therapy.

Do you have breast cancer? Has it been 3 years or more since your primary treatment? If so, you may be able to take part in a research study to help us learn whether there are pre-treatment factors that impact quality of life and function after treatment. Compensation provided.

If you or your child has been diagnosed with acute lymphoblastic leukemia (ALL), you or they might be able to take part in a research study. This study aims to understand why there are differences in outcomes in adolescents and young adults treated for ALL.