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Research Studies

UNC-Chapel Hill Division of Gastroenterology and Hepatology

44 studies match your search
Not currently enrolling

Individualized Diet Elimintation for Treatment of Eosinophilic Esophagitis (EoE)

To see if a new method for identifying food allergies works in determining what foods trigger an allergic condition of the esophagus (eosinophilic esophagitis EoE) and therefore can help treat EoE if they are removed from your diet.

Age & Gender
  • 16 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
  • Stomach, Digestion and Gut Health
  • Ear, Nose, and Throat
Open

EoE Tooth Fairy Study: Environmental Risk Factors for Eosinophilic Esophagitis (EoE)

Do you have any of your baby teeth or are you a parent who has kept your child's baby teeth? Are you a young adult or a parent of a child age 25 or under? Did you know scientists can learn all about different medications, foods, and environmental exposures in a child's early life from their teeth? You may be able to take part in a research study to learn what factors increase children's risk of developing EoE (eosinophilic esophagitis)! We are looking for children and young adults (age 0-25) with or without EoE to volunteer. Compensation will be provided.

Age & Gender
  • 0 years ~ 25 years
  • Male, Female, Gender Inclusive
Study Interest
  • Child and Teen Health
  • Environment
  • Healthy Volunteer or General Population
  • and 5 more
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Dysphagia in College Students

We are doing a survey to learn about swallowing problems, like trouble swallowing food or drinks, in college students. The survey asks questions to see how often these problems happen and what students do to manage them. This will help us understand more about these issues and raise awareness so students can get help if needed.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
  • Healthy Volunteer or General Population
  • UNC Students (undergrad, grad, professional)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

IBD-BOOM

The primary endpoint for this study is subjects achieving either a decrease in Urgency Numeric Rating Scale (NRS) score of ≥ 2 points, or a decrease in score of ≥ 30%, at 12 weeks. Success is defined as ≥ 50% of enrolled subjects meeting the primary endpoint.

Age & Gender
  • 18 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

MONITOR

1) Assess and compare adherence to IV and subcut vedolizumab maintenance therapy in patients with IBD using a novel remote monitoring system. 2) Assess symptom response to vedolizumab post induction (week 6-8) and during maintenance therapy (week 26) using a novel remote monitoring system. 3) Assess time to response to vedolizumab during induction (weeks 0-6) using a novel remote monitoring system.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Eosinophilic Gastrointestinal Disease Registry (CEGIR 7801)

The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) is doing this study because they want to learn more about eosinophilic gastrointestinal disorders (EGIDs).

Age & Gender
  • 3 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Allergy
  • Stomach, Digestion and Gut Health
  • Ear, Nose, and Throat
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

COLOR UC

The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Ulcerative Colitis.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

CHROMA CD

The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Crohn's disease.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

AI Pathology Study

We are studying how to make medical test results easier for patients to understand. Pathology reports, which explain what doctors find in tissue samples, are often written for medical professionals and can be hard for patients to read. In this study, we are testing whether artificial intelligence (AI) can help explain these reports in plain language. Patients having a routine screening procedure will read a sample report with or without an AI-generated explanation. Then they will answer questions about how well they understood the report and how they felt about it. We want to learn if using AI helps people better understand their health information and feel more confident making decisions. This will help improve the way test results are shared in the future.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
  • Healthy Volunteer or General Population
  • Mental and Emotional Health
  • Opinions and Perceptions
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Health and Eating Characteristics in the General Population

The purpose of this project is to advance understanding of the relationship of food and eating characteristics with gastrointestinal symptoms on a population level, by examining the frequency, associated factors, and quality of life and emotional effects of eating-associated gastrointestinal symptoms.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
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