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Research Studies

UNC-Chapel Hill Division of Gastroenterology and Hepatology

39 studies match your search
By physician referral or invitation only

Biomarkers and Liver Transplant Outcomes Among Adults with Hepatocellular Carcinoma

To understand the relationship between biomarkers (found in the blood) and health outcomes among adults diagnosed with hepatocellular carcinoma who are receiving a liver transplant.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Liver)
  • Stomach, Digestion and Gut Health
  • Transplant
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

The Rome V Global Epidemiology and Validation Survey

To (1) test the Rome V Diagnostic Questionnaire, a new version of a questionnaire designed to assess the presence of 25 different Disorders of Gut-Brain Interaction (DGBI), (2) estimate the population prevalence of each of these 25 disorders in the adult population of different countries, (3) evaluate which demographic and personal factors are associated with having these DGBI, and (4) assess their impact on quality of life and emotional wellbeing.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Mirikizumab in the Treatment of Chronic Inflammatory Conditions of the Pouch

Assess the clinical response to treatment with mirikizumab among patients with chronic inflammatory conditions of the pouch using standardized outcome assessments.

Age & Gender
  • 18 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Collection of Biospecimens for Patients with Hepatobiliary Malignancies

To create a biorepository for future research studies to better improve patient treatment in care for patients with liver cancer and liver diseases

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Gray Repository

• To provide investigators in the Division of Gastroenterology with the sources of clinical information for basic research and clinical studies of inflammatory bowel diseases. • To provide optimal and standardized collection of stool for such studies.

Age & Gender
  • 18 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Effect of Vedolizumab and Tofacitinib Combination Therapy in Adults with Moderately to Severely Active Ulcerative Colitis

To determine the effect of dual targeted therapy with an anti-integrin (vedolizumab [VDZ]) and a Janus kinase (JAK) inhibitor (tofacitinib [TOF]) on clinical remission.

Age & Gender
  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Dysphagia in College Students

We are doing a survey to learn about swallowing problems, like trouble swallowing food or drinks, in college students. The survey asks questions to see how often these problems happen and what students do to manage them. This will help us understand more about these issues and raise awareness so students can get help if needed.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
  • Healthy Volunteer or General Population
  • UNC Students (undergrad, grad, professional)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

SC Risa

The objective of this study is to assess the efficacy, safety, and tolerability of RZB SC induction treatment in comparison with placebo in subjects with moderately to severely active CD.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Salix pouch

Demonstrate the safety and feasibility of rifaximin in the prevention of recurrent pouchitis after an initial episode of acute pouchitis.

Age & Gender
  • 18 years ~ 74 years
  • Male, Female, Gender Inclusive
Study Interest
  • Stomach, Digestion and Gut Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

A study of the personal significance of different body symptoms

To examine the personal significance or clinical concerns among different individuals associated with having various gastrointestinal symptoms, as reflected in self-reported bothersomeness, life interference and potential for needing medical attention for those symptoms. Also to evaluate associated factors such as the symptom-related quality of life effects and impact on psychological wellbeing.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
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