To understand the relationship between biomarkers (found in the blood) and health outcomes among adults diagnosed with hepatocellular carcinoma who are receiving a liver transplant.
To (1) test the Rome V Diagnostic Questionnaire, a new version of a questionnaire designed to assess the presence of 25 different Disorders of Gut-Brain Interaction (DGBI), (2) estimate the population prevalence of each of these 25 disorders in the adult population of different countries, (3) evaluate which demographic and personal factors are associated with having these DGBI, and (4) assess their impact on quality of life and emotional wellbeing.
Assess the clinical response to treatment with mirikizumab among patients with chronic inflammatory conditions of the pouch using standardized outcome assessments.
To create a biorepository for future research studies to better improve patient treatment in care for patients with liver cancer and liver diseases
• To provide investigators in the Division of Gastroenterology with the sources of clinical information for basic research and clinical studies of inflammatory bowel diseases. • To provide optimal and standardized collection of stool for such studies.
To determine the effect of dual targeted therapy with an anti-integrin (vedolizumab [VDZ]) and a Janus kinase (JAK) inhibitor (tofacitinib [TOF]) on clinical remission.
We are doing a survey to learn about swallowing problems, like trouble swallowing food or drinks, in college students. The survey asks questions to see how often these problems happen and what students do to manage them. This will help us understand more about these issues and raise awareness so students can get help if needed.
The objective of this study is to assess the efficacy, safety, and tolerability of RZB SC induction treatment in comparison with placebo in subjects with moderately to severely active CD.
Demonstrate the safety and feasibility of rifaximin in the prevention of recurrent pouchitis after an initial episode of acute pouchitis.
To examine the personal significance or clinical concerns among different individuals associated with having various gastrointestinal symptoms, as reflected in self-reported bothersomeness, life interference and potential for needing medical attention for those symptoms. Also to evaluate associated factors such as the symptom-related quality of life effects and impact on psychological wellbeing.