Have you been diagnosed with Eosinophilic Esophagitis (EoE) and therapies you've tried don't work, or you aren't interested in taking drugs to treat your EoE? Are you willing to modify your diet to exclude certain foods for 8 weeks? If so, then you may be eligible to participate in a study to see if an individualized diet elimination therapy works to treat EoE.
Do you suffer from occasional heartburn (called "episodic heartburn)? Have you experienced heartburn for at least 6 months? Is your main (worst) symptom a burning sensation (heartburn) in your chest and throat (behind the breastbone). If so, you may be eligible to participate in a research study to find out if an investigational drug is effective at reducing heartburn. Compensation provided.
Do you keep your child's baby teeth? Are you a parent of a child under age 18? Did you know scientists can learn all about different medications, foods, and environmental exposures in a child's early life from their teeth? You may be able to take part in a research study to learn what factors increase children's risk of developing EoE (eosinophilic esophagitis)! We are looking for parents of children with EoE as well as parents of healthy children to volunteer. Compensation will be provided.
Do you have difficulty swallowing abdominal pain, nausea, vomiting, diarrhea, weight loss, and bloating? Do you have chest pain and heartburn that isn't responding to medication? Do you have eosinophilic gastritis or gastroenteritis (EG/EGE)? If so you may be able to participate in a new research study to find out if a new drug can successfully treat EG/EGE.
To see if a drug administered via injection (dupilumab) is safe and effective at reducing eosinophilic inflammation in the stomach of participants with eosinophilic gastritis (EG)/ eosinophilic gastroenteritis (EGE).
Are you 55 years or older and are scheduled at a UNC Healthcare facility for your first colonoscopy? You may be eligible to participate in a research study that is testing if a stool test (and optional blood test) can detect the presence of colorectal cancer. Compensation is provided.
To determine if a new, minimally invasive device can collect and detect tissue surface cells from the esophagus without sedation. For patients undergoing standard of care, screening upper endoscopy for Gastroesophageal Reflux Disease (GERD).
We want to learn if a new, minimally invasive device can collect and detect tissue surface cells from the esophagus without sedation.
The purpose of the study is to see if a blood test called GuardantLUNAR-2 can help detect colorectal cancer or other diseases. The main goal of ECLIPSE is to collect health information and blood samples from people who are at average risk for colorectal cancer and are scheduled to have a colonoscopy screening test.
Have you been recently diagnosed with colorectal cancer? You may be eligible for a study examining if stool or blood can be used to detect colon cancers as early or earlier than colonoscopy.