Do you have Primary Sclerosing Cholangitis (PSC)? Do you experience symptoms of PSC? If yes, please contact us to screen for this study. We want to interview patients with PSC and learn about your symptoms. This work will help us select, modify or develop patient-reported PSC Symptom surveys to use in future studies and trials of PSC.

Have you been diagnosed with Eosinophilic Esophagitis (EoE) and therapies you've tried don't work, or you aren't interested in taking drugs to treat your EoE? Are you willing to modify your diet to exclude certain foods for 8 weeks? If so, then you may be eligible to participate in a study to see if an individualized diet elimination therapy works to treat EoE.

Do you keep your child's baby teeth? Are you a parent of a child under age 18? Did you know scientists can learn all about different medications, foods, and environmental exposures in a child's early life from their teeth? You may be able to take part in a research study to learn what factors increase children's risk of developing EoE (eosinophilic esophagitis)! We are looking for parents of children with EoE as well as parents of healthy children to volunteer. Compensation will be provided.

Do you have difficulty swallowing abdominal pain, nausea, vomiting, diarrhea, weight loss, and bloating? Do you have chest pain and heartburn that isn't responding to medication? Do you have eosinophilic gastritis or gastroenteritis (EG/EGE)? If so you may be able to participate in a new research study to find out if a new drug can successfully treat EG/EGE.

To see if a drug administered via injection (dupilumab) is safe and effective at reducing eosinophilic inflammation in the stomach of participants with eosinophilic gastritis (EG)/ eosinophilic gastroenteritis (EGE).

Are you 55 years or older and are scheduled at a UNC Healthcare facility for your first colonoscopy? You may be eligible to participate in a research study that is testing if a stool test (and optional blood test) can detect the presence of colorectal cancer. Compensation is provided.

To determine if a new, minimally invasive device can collect and detect tissue surface cells from the esophagus without sedation. For patients undergoing standard of care, screening upper endoscopy for Gastroesophageal Reflux Disease (GERD).

Have you been diagnosed with Barrett's Esophagus or Esophageal Adenocarcinoma? If so, you may be able to participate in a research study to find out if a new, minimally invasive device can collect cells from your esophagus without the need for sedation. Compensation provided.

Are you scheduled at a UNC Healthcare facility for a routine screening colonoscopy? You may eligible to participate in a voluntary research study finding out if a blood test can help detect colorectal cancer.

The purpose of this study is to determine if stool or blood can be used to detect colon cancers as early or earlier than colonoscopy. The researchers plan to use these samples to learn about specific proteins (also known as biomarkers) that may indicate colon polyps, colon cancer or an increased risk of developing colon cancer. In order to learn more about preventing and detecting colon and rectal cancer, we are collecting samples from subjects with colorectal cancer who have not received any treatment.